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Bingshun Wang on Muck Rack

Bingshun Wang

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Articles

Lipid metabolic reprogramming of macrophage by host APOBEC3 deficiency enhances anti-tumor immunity

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By Yuqi Yang, Fanglin Li, Yi Liu, Chen Chen, Danyang Cui, Yiru Long, Xiaolu Yu, Jianhua Sun, JING CHEN, Nan Liu, Bingshun Wang, Likun Gong, Mozi Lei, Jiangling Lu
| Nature Verified
Abstract Tumour-associated macrophages are an indispensable part of the tumour immune microenvironment, exhibiting phenotypic and functional plasticity that enables them to play an important role in modulating the immune response. A large number of RNA editing events have been identified during macrophage functional remodelling. APOBEC3 is a well-known family of base-editing enzymes, but whether and how it regulates macrophage function is unclear.
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