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Biswajit Das on Muck Rack

Biswajit Das

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Articles

Synergies and trade-offs in the heat shock response mechanism

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By Rupal Chauhan, Biswajit Das, Amrita Vishwa Vidyapeetham
| PLOS
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Chauhan R, Das B, Sharma AK (2026) Synergies and trade-offs in the heat shock response mechanism. PLoS Comput Biol 22(9): e1014729. https://doi.org/10.1371/journal.pcbi.1014729 Editor: Christoph Kaleta, Christian Albrechts Universitat zu Kiel, GERMANY Received: October 6, 2025; Accepted: August 17, 2026; Published: September 2, 2026 Copyright: © 2026 Chauhan et al.
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Slow RNAPII elongation enhances naive pluripotency rewiring while maintaining high replication fork speed

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By En-Ze Li, Jing Wang, Jiaxi Li, Sara Martin-Virgala, Joana Segura, Alicia Gallego, Ran Tong, Jesús Rafael Rodríguez-Aguilera, Biswajit Das, Javier Isoler-Alcaraz, Carlos Gallego-García, shraddha shinde, Andrei Chabes, Lothar Schermelleh, Maria Leticia Gomez, María Gómez, Sara Tur-Gracia, Magdalena M. Maslon
| Science Magazine Verified
Abstract DNA replication and transcription must be intricately coordinated as both machineries navigate the same chromatin landscape to ensure genome stability and proper cell function. Here, we show that altering their elongation rates—specifically, slowed transcriptional elongation alongside rapid replication fork progression—does not elicit replicative stress.
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Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly

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By Zishuo Yu, Pradeep Sathyanarayana, Cong Liu, Joel Tan, Pan Yang, Biswajit Das, Side Hu, Xiaoyi Fan, Chenggong Ji, Sandra K. Weller, Mrinal Shekhar, Donald M. Coen, Philip J. Kranzusch, Joseph J. Loparo, Jonathan Abraham
| Cell Press Verified
Keywords herpesvirus helicase primase polymerase antiviral DNA replication Introduction Herpesviruses are a large group of enveloped double-stranded DNA (dsDNA) viruses that contain many highly prevalent human pathogens.1 There are three subfamilies of human herpesviruses—α, β, and γ.1 Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily, with many members establishing lifelong latency in sensory neurons.
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