Boris Bartholdy
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MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
Main text (Cancer Cell 39, 529–547.e1–e7; April 12, 2021) We, the authors of this article, investigated how MDMX overexpression drives the transition from preleukemia to acute myeloid leukemia across multiple mouse models. Following publication, we were alerted to duplications in the flow cytometry plots in Figure 3E.
Abstract IA18: The PI3K isoforms in myeloid leukemia and hematopoietic stem cells
Oral Presentations - Invited Abstracts Shayda Hemmati, Taneisha Sinclair, Meng Tong, Boris Bartholdy, Rachel Okabe, Kristina Ames, Leanne Ostrodka, Tamanna Haque, Imit Kaur, Anupriya Agarwal, Jean Zhao, Thomas Roberts and Kira Gritsman DOI: 10.1158/1557-3125.PI3K-mTOR18-IA18 Published October 2020 Abstracts: AACR Special Conference on Targeting PI3K/mTOR Signaling; November 30-December 8, 2018; Boston, MA Abstract The Class IA PI3 kinase isoforms (p110α, β, and δ) transduce many growth factor...
ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα
The transcription factor C/EBP? is essential for myeloid differentiation and is frequently dysregulated in acute myeloid leukemia. Although studied extensively, the precise regulation of its gene by upstream factors has remained largely elusive. Here, we investigated its transcriptional activation during myeloid differentiation.
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