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A roadmap for establishing institutional readiness for cellular therapies targeting solid tumours and autoimmune diseases

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By Sarah Childs, David Ma, Elizabeth Houghton, Rasha Cosman, Jennifer Massey, Venessa T. Chin, Amanda L. McLaughlin, Simon Goodwin, Barbara Sheehan Withers, Callie Noakes, Annabel Horne, Jessica Boyd, Dion Forstner, Anthony J Rodrigues, Geeta Sandhu, Karim Ibrahim, Chloe Martin, Benjamin Kwan, Hergen Buscher, Philip J. Cunningham, Anthony M. Joshua, Laila Girgis, Ben Tran, Jayesh Desai, Simon Harrison, John Moore, Jia Liu, Valerie Valencia, Aaron O’Grady, Simone Kay Jensen, Helen Tao, Paul Preisz, Nicolas De Luca
| Nature Verified
Abstract Adoptive cellular therapies have revolutionised treatment of haematological malignancies and demonstrate potential in solid tumours and autoimmune disease. Real-world implementation remains limited by biological, logistical, and manufacturing barriers, restricting global uptake despite a rapidly expanding clinical trial portfolio. Effective implementation requires national and institutional readiness, multidisciplinary collaboration, scalable manufacturing, and robust infrastructure.
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