Barbara Sheehan Withers
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A roadmap for establishing institutional readiness for cellular therapies targeting solid tumours and autoimmune diseases
Abstract Adoptive cellular therapies have revolutionised treatment of haematological malignancies and demonstrate potential in solid tumours and autoimmune disease. Real-world implementation remains limited by biological, logistical, and manufacturing barriers, restricting global uptake despite a rapidly expanding clinical trial portfolio. Effective implementation requires national and institutional readiness, multidisciplinary collaboration, scalable manufacturing, and robust infrastructure.
Efficacy of bortezomib, cyclophosphamide and dexamethasone in cardiac AL amyloidosis
Abstract Cardiac light chain (AL) amyloidosis is a condition with a very poor prognosis. We report a retrospective analysis comparing the traditional melphalan and dexamethasone protocol with cyclophosphamide, bortezomib and dexamethasone in late-stage cardiac AL amyloidosis. The primary end points were overall survival and haematological response. Both regimens provided meaningful responses in this difficult to treat patient group.
Pregnancy post autologous stem cell transplant with BEAM conditioning for multiple sclerosis
Show all authors Sophie Chatterton Department of Neurology, St Vincent’s Hospital Sydney, Darlinghurst, NSW, Australia/St Vincent’s Clinical School, University of New South Wales, Darlinghurst, NSW, Australia View ORCID profile See all articles by this author , Barbara Withers St Vincent’s Clinical School, University of New South Wales, Darlinghurst, NSW, Australia/Department of Haematology and Bone Marrow Transplantation, St Vincent’s Health Network, Darlinghurst, NSW, Australia/Kinghorn...
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