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Calum Roberts on Muck Rack

Calum Roberts

United Kingdom
As seen in: Color Research & Application, SAGE Publishing, JAMA (The Journal of the American Medical Association), The New England Journal of Medicine, BioRxiv, Pediatrics, Information Age, The Journal of Pediatrics
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Articles

Rapid oxygen titration following cardiopulmonary resuscitation mitigates cerebral overperfusion and striatal mitochondrial dysfunction in asphyxiated newborn lambs - Shiraz Badurdeen, Robert Galinsky, Calum T Roberts, Kelly J Crossley, Valerie A Zahra, Al

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By Shiraz Badurdeen, Robert Galinsky, Calum Roberts, Kelly J. Crossley
| SAGE Publishing
Introduction Cardiopulmonary resuscitation (CPR) of neonates with severe perinatal asphyxia currently focuses on rapid restoration of the circulation to limit ongoing hypoxic-ischemic brain injury.1,2 Given the challenges in conducting adequately powered trials of CPR in neonates, international recommendations rely on transitional animal models to guide practice.1 Current guidelines recommend increasing the fraction of inspired oxygen (FiO2) to 100% if chest compressions are required to...
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Rapid oxygen titration following cardiopulmonary resuscitation mitigates cerebral overperfusion and striatal mitochondrial dysfunction in asphyxiated newborn lambs

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By Shiraz Badurdeen, Robert Galinsky, Calum Roberts, Kelly J. Crossley
| BioRxiv
Abstract Asphyxiated neonates must have oxygenation rapidly restored to limit ongoing hypoxic-ischemic injury. However, the effects of transient hyperoxia after return of spontaneous circulation (ROSC) are poorly understood. We randomly allocated acutely asphyxiated, near-term lambs to cardiopulmonary resuscitation in 100% oxygen (standard oxygen, n=8) or air (n=7) until 5 minutes after ROSC, or to resuscitation in 100% oxygen immediately weaned to air upon ROSC (rapid-wean, n=7).
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Placental Perfusion Rather Than Placental Transfusion-Key to Umbilical Cord Management at Birth?

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By Calum Roberts, Monash Newborn
| JAMA (The Journal of the American Medical Association) Verified
The best approach to management of the umbilical cord at birth has been a topic of discussion over centuries, with documented opinions from historical figures, such as Aristotle and Erasmus Darwin.1 This has not yet diminished the opportunity for new insights. Kuehne et al2 compare 2 approaches in a population of infants with very low birth weight born by cesarean delivery in a randomized clinical trial conducted at a single German tertiary center.
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