Cameron T. Flower on Muck Rack

Cameron T. Flower

As seen in: Cell Press
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Articles

Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity

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By Tigist Y. Tamir, Shreya Chaudhary, Annie Li, Sonia Trojan, Cameron T. Flower, Paula Vo, Yufei Cui, Jeffrey Davis, Rachit S Mukkamala, Francesca N. Venditti, Alissandra L. Hillis, Alex Toker, Jessica B. Spinelli, Norman Kennedy, Roger Davis, Forest M. White
| Cell Press
Keywords metabolism cell signaling oxidative stress response obesity phosphoproteomics metabolomics computational modelling GSTP1 IDH1 UMPS Introduction Cellular adaptation to environmental and metabolic stress relies on the precise coordination of signaling and metabolic networks.
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Signaling and transcriptional dynamics underlying early adaptation to oncogenic BRAF inhibition

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By Cameron T. Flower, Chunmei Liu, Hui-Yu Chuang, Xiaoyang Ye
| biorxiv.org
Abstract A major contributor to poor sensitivity to anti-cancer kinase inhibitor therapy is drug-induced cellular adaptation, whereby remodeling of signaling and gene regulatory networks permits a drug-tolerant phenotype.
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High-Density, Targeted Monitoring of Tyrosine Phosphorylation Reveals Activated Signaling Networks in Human Tumors

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By Lauren Stopfer, Cameron T. Flower, Aaron S. Gajadhar, Bhavin Patel
| cancerres.aacrjournals.org
Translational Science Lauren E. Stopfer, Cameron T. Flower, Aaron S. Gajadhar, Bhavin Patel, Sebastien Gallien, Daniel Lopez-Ferrer and Forest M. White DOI: 10.1158/0008-5472.CAN-20-3804 Published May 2021 This article requires a subscription to view the full text. You may purchase access to this article or login to access your subscription using the links below. Abstract Tyrosine phosphorylation (pTyr) plays a pivotal role in signal transduction and is commonly dysregulated in cancer.
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