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Carla Jones on Muck Rack

Carla Jones

As seen in: Nature, New York Post, News.com.au, Elsevier, Patch, Gatton, Lockyer & Brisbane Valley Star, Aesthetics
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Articles

Single-cell RNA sequencing of terminal ileal biopsies identifies signatures of Crohn’s disease pathogenesis

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By Monika Krzak, Tobi Alegbe, Gareth-Rhys Jones, Mennatallah Ghouraba, Michelle Strickland, Bradley Harris, Reem Satti, Kenneth Arestang, Lucia Ramirez-Navarro, Nilanga Nishad, Marcus Tutert, Matiss Ozols, Guillaume Noell, Steven Leonard, Moritz J. Przybilla, Ciro Ramirez Suastegui, Eleonora Khabirova, Tong Deng, Hanna Najgebauer, Velislava N. Petrova, Carla Jones, Noor Wana, May Xueqi Hu, Jason Skelton, Jasmin Ostermayer, Yong Gu, Wendy Garri, Biljana Brezina, Daniele Corridoni, Miles Parkes, Vivek N. Iyer, Cristina Martin Verified, Rebecca McIntyre, Tim Raine, Carl A. Anderson
| Nature Verified
Abstract Crohn’s disease (CD) is a chronic inflammatory bowel disease exhibiting substantial heterogeneity in clinical presentation and response to therapy. To explore its molecular basis, we developed IBDverse, a large single-cell RNA sequencing (scRNA-seq) dataset of terminal ileal biopsies, profiling over 1.1 million cells from 111 patients with CD and 232 healthy controls.
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Trans-eQTL mapping prioritises USP18 as a negative regulator of interferon response at a lupus risk locus - Nature Communications

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By Anneke Brümmer, Robert Warmerdam, Ana Laura Hernández-Ledesma, Joshua Chiou, Joseph C. Maranville, Michael Turchin, eQTLGen Consortium, Lude Franke, Urmo Võsa, Carla Jones, Gosia Trynka, Kai Kisand, Sven Bergmann Verified
| Nature Verified
Abstract Although genome-wide association studies have provided valuable insights into the genetic basis of complex traits and diseases, translating these findings to causal genes and their downstream mechanisms remains challenging. We performed trans expression quantitative trait locus (trans-eQTL) meta-analysis in 3734 lymphoblastoid cell line samples, identifying four robust loci that replicated in an independent multi-ethnic dataset of 682 individuals.
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Philosophy in Fabric: Galih Podo by Batik Artist Sapuan

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By Carla Jones
Requiring over two years to complete (2020-22), Galih Podo was created by applying layers of liquid wax by hand, through small brass vessels called canting, and then dying the fabric in phases. Galih Podo is a remarkable illustration of hand-made batik in a world of increasingly mass-produced textiles.
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