Skip To Main Content
Caroline Bartman on Muck Rack

Caroline Bartman

As seen in: The New York Times, Nature, Yahoo, BioRxiv, Cell Metabolism, Cell Press, RealClear Politics, The Journal of Immunology
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Caroline

Contact Caroline, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Metabolic and transcriptional plasticity supports CD8 + T cell resilience and anti-tumor immunity under nutrient stress

|
By Michael Scaglione, Montana S. Knight, Krittin Trihemasava, Anne-Sophie Archambault, Juhee Oh, Erin Tanaka, Elise Hall, Tran Ngoc Van Le, Caleb Lines, Brian P Goldspiel, Hossein Fazelinia, Clemence Queriault, Lucien H. Turner, Tanay Parnaik, Jimmy Xu, Morgan Brown, Oishi Bardhan, Jessie E. Axsom, Frederick C. Bennett, Lynn Spruce, Caroline Bartman, Clementina Mesaros, Ramon I. Klein Geltink, Crystal S. Conn, Will Bailis
| Cell Press Verified
Keywords T cells CD8+ T cells T cell exhaustion anti-tumor immunity stress adaptation translation polysome profiling nutrient stress mTOR integrated stress response GCN2 HRI ATF4 CEBPG tumor-infiltrating lymphocyte immunometabolism amino acids Get full text access Log in, subscribe or purchase for full access. References 1. Palm, W. ∙ Thompson, C.B. Nutrient acquisition strategies of mammalian cells Nature. 2017; 546:234-242 2. Zhu, J.
Open in Who Shared Issue with article?

Lactate homeostasis is maintained through regulation of glycolysis and lipolysis

|
By Won Dong Lee, Daniel R. Weilandt, Lingfan Liang, Michael R. MacArthur, Natasha Jaiswal, Olivia Ong, Charlotte Mann, Qingwei Chu, Craig Hunter, Rolf-Peter Ryseck, Wenyun Lu, Anna M. Oschmann, Alexis J. Cowan, Tara TeSlaa, Caroline Bartman, Cholsoon Jang, Joseph A. Baur, Paul M. Titchenell, Joshua D. Rabinowitz
| Cell Metabolism Verified
Keywords lactate metabolism metabolic homeostasis insulin signaling HCAR1 signaling competitive catabolism TCA cycle insulin resistance diabetes mellitus metabolic flux quantitative modeling Get full text access Log in, subscribe or purchase for full access. References 1. Brooks, G.A. The Science and Translation of Lactate Shuttle Theoryy Cell Metab. 2018; 27:757-785 2. Gladden, L.B. Lactate metabolism: a new paradigm for the third millennium J. Physiol. 2004; 558:5-30 3. Zhang, D. ∙ Tang, Z. ∙ Huang, H.
Open in Who Shared Issue with article?

One-carbon unit supplementation fuels tumor-infiltrating T cells and augments checkpoint blockade

|
By Zihong Chen, Caroline Bartman, Xi Xing, Xincheng Xu
| BioRxiv
Abstract Nucleotides perform important metabolic functions, carrying energy and feeding nucleic acid synthesis. Here, we use isotope tracing-mass spectrometry to quantitate the contributions to purine nucleotides of salvage versus de novo synthesis. We further explore the impact of augmenting a key precursor for purine synthesis, one-carbon (1C) units. We show that tumors and tumor-infiltrating T cells (relative to splenic T cells) synthesize purines de novo.
Open in Who Shared Issue with article?
See all 12 articles