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Rescaling of Distance Judgments With Geometric and Contextual Changes
1 Introduction Animals are thought to construct a cognitive map of their environment within the hippocampal formation, enabling flexible navigation to remembered goals (O'Keefe and Dostrovsky 1971; Tolman 1948). This notion is supported by evidence that hippocampal lesions impair navigation to hidden goals in both rats and humans (Maguire et al. 2006).
Disrupted hippocampal replay is associated with reduced offline map stabilization in an Alzheimer’s mouse model
Keywords Alzheimer's disease hippocampus place cells stability replay memory electrophysiology behavior Introduction The hippocampus plays a central role in memory for places and events, spatial navigation, and systems-level memory consolidation.1,2,3,4 A key functional basis of the hippocampal role in navigation and spatial memory is the stable, spatially selective activity of place cells, primarily found in hippocampal regions CA3 and CA1.5,6 The population activity of these cells is...
Impact of symmetry in local learning rules on predictive neural representations and generalization in spatial navigation
Citation: Keck J, Barry C, Doeller CF, Jost J (2025) Impact of symmetry in local learning rules on predictive neural representations and generalization in spatial navigation. PLoS Comput Biol 21(6): e1013056. https://doi.org/10.1371/journal.pcbi.1013056 Editor: Suhita Nadkarni, IISER P: Indian Institute of Science Education Research Pune, INDIA Received: July 24, 2024; Accepted: April 14, 2025; Published: June 23, 2025 Copyright: © 2025 Keck et al.
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