Chek Kun Tan on Muck Rack

Chek Kun Tan

As seen in: Cell Press
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Articles

Cell Press: Cell Press

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By Hwee Ying Lim, Sheau Yng Lim, Chek Kun Tan, Chung Hwee Thiam, Daniel Carbajo, Peter See, Svetoslav Chakarov, Xiao Wang, Louise Johnson, Arijit Biswas, Josephine Lum, Chui Yee Fong, Ariff Bongso
| Cell Press Verified
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Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen

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By Nanyang Technological, Hwee Ying Lim, Sheau Yng Lim, Chek Kun Tan
| Cell Press Verified
The maintenance of appropriate arterial tone is critically important for normal physiological arterial function. However, the cellular and molecular mechanisms remain poorly defined. Here, we have shown that in the mouse aorta, resident macrophages prevented arterial stiffness and collagen deposition in the steady state.
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