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ArticleVolume 38, Issue 4p673-693.e17 Affiliations & Notes 1China National Center for Bioinformation and Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China 2State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China 3University of Chinese Academy of Sciences, Beijing 100049, China 4State Key Laboratory of Cognitive Science and Mental Health, Institute of Biophysics, Chinese Academy of...
Keywords aging senescence biomarker stem cell intervention rejuvenation gene editing FOXO3 brain reproductive system Introduction Aging, an unavoidable trajectory, precipitates tissue and physiological deterioration, leading to conditions such as neurodegenerative diseases, reduced fertility, and cardiovascular problems.1,2,3,4,5,6,7,8,9,10,11 Emerging research implicates the decline of stem cell populations and a diminishing regenerative potential as pivotal to the aging...
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