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Pradeep Reddy

As seen in: Nature, Frontiers, BMC Genomics, Science Magazine, BioRxiv, Cell Metabolism, Cell Stem Cell, Cell Press, The Student Room, DataQuest India and
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Articles

ZNF512B safeguards genome integrity at regulatory regions to repress the SASP and inflammation

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By Sanjeeb Kumar Sahu, Sebastian Memczak, Sudhir Thakurela, Jinlong Y. Lu, Priya Gupta, Yingzi Zhang, Tomoaki Hishida, Masakazu Kurita, Chao Wang, Yanjiao Shao, April Williams, Vijay K Tiwari, Concepcion Rodriguez Esteban, Pradeep Reddy, Alexander Meissner, Mo Li, Naresh Mutukula, Alex Hirano, Max Shokhirev
| Cell Stem Cell Verified
Keywords genome integrity DNA repair senescence senescence-associated secretory phenotype SASP inflammation CRISPR-Cas9 screening ZNF512B chromatin remodeling amyotrophic lateral sclerosis neuromuscular organoids Get full text access Log in, subscribe or purchase for full access. References 1. Di Micco, R. ∙ Krizhanovsky, V. ∙ Baker, D. ... Cellular senescence in ageing: from mechanisms to therapeutic opportunities Nat. Rev. Mol. Cell Biol. 2021; 22:75-95 2. Eggert, T. ∙ Wolter, K. ∙ Ji, J. ...
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Mesenchymal drift: A convergent framework for the hallmarks of aging

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By Jinlong Y. Lu, William B. Tu, Shuai Ma, Zaijun Ma, Ivan Imaz-Rosshandler, Mingxi Weng, Jing Qu, Concepcion Rodriguez Esteban, Pradeep Reddy, Guang-Hui Liu
| Cell Press Verified
Keywords aging epithelial-to-mesenchymal transition endothelial-to-mesenchymal transition rejuvenation biomarkers partial reprogramming Yamanaka factors fibrosis cellular identity and plasticity geroscience Introduction Aging biology is commonly framed through a set of canonical “hallmarks.” Since their original formulation,1 these hallmarks have expanded from nine to twelve2 and more recently to fourteen,3 reflecting both the growing complexity of aging biology and the field’s effort to...
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Vitamin C inhibits ACSL4 to alleviate ferro-aging in primates

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By Lixiao Liu, Zikai Zheng, Wanbang You, Peng Yang, Yifan Wen Verified, Yicheng Qiao, Shuai Ma, Shuo Zhang, Gang Xu, Chencan Ma, Ao Tian, Mengmeng Jiang, Tongtong Zhang, Lingling Geng, Jingyi Li, Xiaoyan Sun, Feibo Wang, Muzhao Xiong, Yuanhan Yang, Xiaoyong Lu, Xiaoyu Jiang, Xueda Dong, Zhiyi Zhang, Ying Huang, Baohu Zhang, Qin Qiao, Shuhui Sun, Yanling Fan, Yusheng Cai, Kaowen Yan, Yiyuan Zhang, Ying Jing, Yaobin Jing, Qiaoran Wang, Jinghui Lei, Ansheng Tan, Zichu Han, Pradeep Reddy, Amin Haghani, Concepcion Rodriguez Esteban, Feng Zhang, Zhili Liu, Ning Liu, Si Qi Wang, Steve Horvath, Jiayin Yang, Weiqi Zhang, Jing Qu, Guang-Hui Liu
| Cell Metabolism Verified
ArticleVolume 38, Issue 4p673-693.e17 Affiliations & Notes 1China National Center for Bioinformation and Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China 2State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China 3University of Chinese Academy of Sciences, Beijing 100049, China 4State Key Laboratory of Cognitive Science and Mental Health, Institute of Biophysics, Chinese Academy of...
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