Chris Chen
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Articles by Chris Chen
The new value test for investors: What founders are actually buying when they take your cheque
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Exploring multifaceted mental resilience from the perspectives of sleep and circadian rhythm in healthy adults
Financial disclosure: Prof. Yun Kwok Wing received personal fees from Eisai Co., Ltd., for delivering a lecture, and sponsorship from Lundbeck HK Ltd and Aculys Pharma, Inc. Dr. Joey Wing Yan Chan received personal fee from Eisai Co., Ltd and travel support from Lundbeck HK limited for overseas conferences. The remaining authors declare that the study was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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Gen Z doesn’t need more AI courses, it needs the skills AI can’t replicate
In April 2026, the United States announced 83,387 job cuts. 26 per cent of them named artificial intelligence as the reason, the second consecutive month that AI was the top cited cause. Behind those numbers is a quieter story that is going to shape an entire generation of careers.
Correction to: Scientific Reports https://doi.org/10.1038/s41598-026-48748-0, published online 15 April 2026 The original version of this Article contained error in Equations 1, 2, 3, 5 and 6. The error was a result of a file conversion anomaly. The original html version of the article was correct. The content of the paper remains unchanged with the exception of corrected PDF version.
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Keep tabs on your valuables with Google Pixel Tag
Introducing Google Pixel Tag, our first-ever finder tag. Helpful and secure, it uses Google’s Find Hub network to quickly and easily locate your favorite items. It’s great for your keys, wallet, or even luggage. 1 Tiny but mighty Thin and light, Pixel Tag is made of durable stainless steel that’s designed to resist flexing and cracking, and is IP67 water- and dust-resistant.
Gardez un œil sur vos objets de valeur grâce à Google Pixel Tag
Découvrez le Google Pixel Tag, notre tout premier traqueur. Pratique et sécurisé, il se base sur le réseau Localiser de Google pour vous aider à retrouver vos objets préférés rapidement et facilement. Il est idéal pour vos clés, votre portefeuille ou même vos bagages. 1 Petit, mais puissant Fin et léger, le Pixel Tag bénéficie d’une structure interne en acier inoxydable durable. Il est conçu pour résister à la flexion et aux fissures, et résiste à l'eau et à la poussière (IP67).
5 US venture capital shifts every Southeast Asian founder should be tracking right now
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Effect of Acoramidis on Heart Failure–Related Health Status : A Secondary Analysis of the ATTRibute-CM Randomized Clinical Trial
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Effect of Acoramidis on Heart Failure–Related Health Status: A Secondary Analysis of the ATTRibute-CM Randomized Clinical Trial Supplement 1. Supplement 2. Statistical Analysis Plan Supplement 3. eTable 1. Summary of Definitions Used for Analyses of KCCQ-OS Outcomes eTable 2. Median Participant KCCQ Domain Scores Prior to Initiation of Treatment (Baseline), mITT Population (N = 611) eTable 3.
By Charles F. Sherrod, Marianna Fontana, Julian D Gillmore, Efstathios Kastritis, Joshua Mitchell, Jan Krejci, James Tauras, Peter van der Meer, Chris Chen, Heather Falvey, Jonathan Fox, Francesco Cappelli, Ahmad Masri, Pablo García-Pavía, Mazen Hanna, Brett W. Sperry, Suresh Siddhanti, Jean-François Tamby
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JAMA Cardiology
Capturing omega sign in the clinical assessment of depression by deep learning
Abstract The omega sign is a melancholic facial expression, resembling the Greek letter omega “Ω”. To study static omega sign (visible full-blown Ω-shaped or vertical wrinkles at rest) and dynamic omega sign (newly appearing or deepening) with digital assessment for depression via deep learning, subjects with major depressive disorder (MDD) and controls were invited to take neutral photos and videotaped interviews to study the static and dynamic omega sign, respectively.
When all the capital lands in Singapore and goes nowhere else
In the first half of 2025, something quietly remarkable happened to money in Southeast Asia. Singapore, a city of fewer than six million people, captured about 92% of all startup funding raised across a region of nearly 700 million. In fintech, the figure was 88%. By January 2026, Singapore was pulling in more than 96% of the region’s monthly venture funding. The easy way to read this is as a triumph, and in part it is. I have spent years arguing that Singapore’s deepest asset is trust.
Asia is now buying America and nobody is talking about it - Chris chen
Due to the technical or legal........
Why ‘Singapore washing’ will never be the same
In April, China’s National Development and Reform Commission moved to unwind Meta’s planned US$2 billion acquisition of Manus, the AI-agent startup founded in Beijing that had relocated its headquarters to Singapore in mid-2025. Meta had agreed to buy the company in December. But by late March, co-founders Xiao Hong and Ji Yichao had been barred from leaving China while regulators reviewed the transaction. By the end of April, the deal was blocked.
Singapore is winning the AI race nobody is watching
It is 2028. A Fortune 500 bank in London is deciding where to deploy its first fully autonomous AI agent for credit decisions. The bank has access to the most powerful AI models in the world. Some come from California. Some come from Beijing. Some come from Paris. The capability is no longer the question. What the bank needs is something else. It needs an audit framework that satisfies its regulators in three different countries.
Singapore is winning the AI race nobody is watching
It is 2028. A Fortune 500 bank in London is deciding where to deploy its first fully autonomous AI agent for credit decisions. The bank has access to the most powerful AI models in the world. Some come from California. Some come from Beijing. Some come from Paris. The capability is no longer the question. What the bank needs is something else. It needs an audit framework that satisfies its regulators in three different countries.
While leaders meet in Beijing, families rewrite regional funding
When the leaders of the United States and China met in Beijing on May 14 and 15, 2026, the global press coverage was predictable. Tariffs: Taiwan. Iran. Boeing. The coverage was accurate. It also missed the most important shift in regional capital flows in two decades. For most of the postwar period, Asia’s wealthy operated in tandem with their governments. When governments negotiated trade deals or signed treaties, the wealthy invested in step. The government was the partner that backed the direction.
Predicting acute stress recovery: a resilience index of physiological responses to Trier Social Stress Test
Previous theoretical and empirical research has highlighted the predictive utility of different physiological reactivity and recovery patterns during acute stress for long-term mental health outcomes. Timely identification of mental health risk can be achieved by integrating these multiple temporal responses to characterize adaptive, dynamic resilience factors and then generating a resilience index.
Asia is quietly and quickly buying up America
For 50 years, the direction of cross-border capital between Asia and the United States was largely one-way, with American firms acquiring Asian assets, US capital funding Asian growth and US consumers absorbing Asian production. The pattern was so durable that few stopped to ask whether the direction could one day reverse. In 2025 and the first months of 2026, the direction did reverse – quietly, deliberately and at a scale most analysts have not yet processed.
Designed to hurt Asia, Trump’s tariffs did the opposite
When the Trump administration announced sweeping tariffs on Asian economies on April 2, 2025, the political framing was simple. The tariffs would punish Asian exporters, shrink the US trade deficit and force capital home. Asia was cast as the vulnerable party in a contest the US expected to dominate. The 2025 trade data, however, tells a very different story.
Associations of psychological resilience with macro- and microstructures in NREM and REM sleep in adolescents
Ayuda Buscar en la ayuda Buscar en la ayuda Associations of psychological resilience with macro- and microstructures in NREM and REM sleep in adolescents Chris Xie Chen [1] ; Shirley Xin Li [2] ; Chung Shun Ho [1] ; Joey Wing Yan Chan [1] ; Leo King Wai Chan [1] ; Tatia Mei-Chun Lee [2] ; Yun Kwok Wing [1] ; Ngan Yin Chan [1] [1] Chinese University of Hong Kong [2] University of Hong Kong Localización: International journal of clinical and health psychology, ISSN 1697-2600, Vol. 25, Nº.
How to turn your side hustle into a day job
Your new favourite word: planning. CommBank business banker Mathew Buckland says it’s the most important thing when you’re moving away from the security of a salary. “You’re giving yourself an extra 40 hours a week to work on your business so planning how those 40 hours are going to generate income is key.” Here’s how to make it happen. Look before you leap Before you throw in your day job, take a look at your cash flow.
[2506.19866] GPU-accelerated Modeling of Biological Regulatory Networks
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
A modified at-home methodology for measuring dim light melatonin onset timing in healthy adults
ABSTRACT The goal of this study was to investigate whether a modified at-home dim light melatonin onset (DLMO) assessment would be comparable to the in-laboratory DLMO assessment. Fifty-five participants underwent the at-home DLMO, while 55 age- and sex-matched participants underwent the in-laboratory DLMO assessment.
Dental Veneers: Transforming Your Smile with a Subtle Touch
Chris Chen Medical Technology and Software Blog 2025-02-20 Dental Veneers: Transforming Your Smile with a Subtle Touch Chris Chen Medical Technology and Software Blog 2025-02-20 Chris Chen Medical Technology and Software Blog 2025-02-20 Delightfully Gentle, Extremely Professional. Lumina Dental is the Highest Rated Dentist In Ultimo & Broadway. Book Online Today.
Microglia regulate neuronal activity via structural remodeling of astrocytes
Abstract Neuron-glia interactions play a central role in regulating synaptic transmission and neuronal excitability. Structural plasticity of astrocytes is associated with numerous physiological and pathological conditions, however, the mechanism underlying this process remains unknown. To examine the basis for structural astrocyte plasticity, we used the classic example of the loss of astrocytic processes that takes place in the hypothalamic magnocellular system during chronic high-salt intake.
Level Up: Training Employees to Work Alongside AI
Artificial intelligence (AI) is everywhere and it’s transforming the way we work — yet the speed at which it has emerged means that businesses are struggling to keep up. While 72% of companies have embraced AI, new research shows that a shocking 19% of U.K. employees say they haven’t received any real training on how to use it.
Huge number of UK employees not trained properly on how to work with AI
One in five (19%) UK employees, equating to 6.31 million1 workers, have received no real training from their organisations on how to work and collaborate effectively with AI tools, according to latest findings. The research*, exposes the disconnect: while 70% of UK employees are already using AI in their roles, over a third (34%) admit they lack the necessary soft and human skills to work effectively with these tools.
Almost-scam experience on Upwork: Do not make a contract outside of Upwork
Chris Chen · Follow Published in 行銷羊與律師虎 · 5 min read · -- I started using Upwork for freelance work on December 3, 2020, and I encountered a scam group with such sophisticated techniques for the first time. I decided to share what happened, hoping that translators looking to take on projects on this platform won’t fall for similar scams. Let’s rewind to June 18, 2022. I received a proposal invitation in my inbox. When I clicked on it, I found a company called OKTA Publishers.
Süßes Wunder: Honig kann Blutzucker und Risiko für Herzkrankheiten senken
Mehr als nur Zucker: Jüngste Forschungen bestätigen eine Vielzahl an gesundheitlichen Vorteilen von Honig. Diese treffen allerdings nur auf echten Bienenhonig zu – nicht auf künstlich hergestellten Honig. Obwohl Honig zu 80 Prozent aus Zucker besteht, kann er laut Studien den Blutzuckerspiegel reduzieren und dazu beitragen, Herzkrankheiten, Fettleibigkeit und Diabetes entgegenzuwirken.
Protéger notre thymus : Un organe qui peut se régénérer avec des avantages surprenants
Dans cette série , « Le système immunitaire miraculeux », nous explorons le véritable pouvoir de l’immunité et les organes qui travaillent sans relâche pour protéger le corps. Le thymus, peu connu, est l’un des organes immunologiques les plus essentiels de l’organisme. Il commence à se développer avant la naissance et atteint sa fonction maximale entre 7 et 25 ans.
Efficacy and safety of dofetilide and sotalol in patients with hypertrophic cardiomyopathy - Communications Medicine
Abstract Background Professional society practice guidelines conflict regarding their recommendations of dofetilide (DOF) and sotalol (STL) for treatment of arrhythmias in hypertrophic cardiomyopathy (HCM), and supporting data is sparse. We aim to assess safety and efficacy of DOF and STL on arrhythmias in HCM. Methods This was an observational study of HCM patients treated with DOF or STL for atrial fibrillation (AF) and ventricular arrhythmias (VA).
Protecting Our Thymus: An Organ That Can Regenerate With Surprising Benefits
The little-known thymus gland is one of the body’s most essential immunological organs, beginning to develop before birth and reaching its peak function between the ages of 7 and 25. The thymus is like a military base that trains soldiers—T cells—to battle for the immune system against dangers such as COVID-19 and cancer. Despite its critical role, the thymus gland’s ability to stimulate effective T cell generation declines with age.
Time To Heal: Former Pussycat Doll Jessica Sutta’s Experience With Neurological Symptoms After the Moderna Vaccine
At the height of the COVID-19 pandemic, Jessica Sutta wanted to do what was right. As “a law-abiding citizen,” she felt it was her responsibility to get vaccinated to protect her community and help stop the pandemic. She never expected a negative reaction to the COVID-19 vaccine—one that would dramatically change the course of her life. Sutta spoke with The Epoch Times “American Thought Leaders” host Jan Jekielek about her experience with the COVID-19 vaccine.
Anxiety May Not Be Just in Your Head. It Can Start in Your Heart
Published on May 9, 2023 Written by Yuhong Dong, M.D., Ph.D and Chris Chen Research takes a closer look at the heart-brain axis and how the heart’s signals to the brain may decide how we feel Our body is truly amazing, with two vital organs—the heart and the brain—working together seamlessly to keep us alive and healthy. The heart acts as a pump, tirelessly circulating blood through the vascular system, providing oxygen and nutrients to the brain, lungs, and other organs to function properly.
Anxiety May Not Be Just in Your Head. It Can Start in Your Heart Original
Our body is truly amazing, with two vital organs—the heart and the brain—working together seamlessly to keep us alive and healthy. The heart acts as a “pump,” tirelessly circulating blood through the vascular system, providing oxygen and nutrients to the brain, lungs, and other organs to function properly. Meanwhile, the brain serves as the command center, communicating with the body through the nervous system.
Data for smarter farming practices
By Chris Chen, head of digital transformation, Syngenta Asia-Pacific The world’s food security is under threat. Exacerbated by the pandemic, climate change, and political and economic instability, many countries are facing food shortages and rising prices. The increased frequency of extreme weather events such as droughts, floods and heat waves are damaging crops and destroying harvests, causing significant impact on yields and financial losses for farmers.
Why it's crucial to ease risk management in Singapore
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1 Food Can Help Obese People Avoid Diabetes and Heart Disease
If you’re obese, including almonds in your daily diet can help to prevent diabetes and heart disease. Almonds are popular and affordable. Aside from being delicious, they also contain antioxidants, promote skin health, lower cholesterol, and aid digestion. But for obese people, almonds have far more benefits and should be incorporated into their daily diet.
El inesperado efecto de la miel en la diabetes
Sí, no está leyendo mal: La miel puede reducir el azúcar en sangre a pesar de contener aproximadamente un 80 por ciento de azúcar. Además de reducir el azúcar en sangre, la miel puede aumentar la inmunidad y ralentizar el proceso de envejecimiento. Recientemente, los investigadores han demostrado que la miel tiene una amplia gama de ventajas imprevistas.
Le miel peut-il prévenir le diabète?
Non, il n’y a pas d’erreur : le miel peut réduire le taux de sucre dans le sang bien qu’il soit composé d’environ 80% de sucre. En plus de réduire la glycémie, le miel peut renforcer l’immunité et ralentir le processus de vieillissement. Récemment, des chercheurs ont montré que le miel présente un large éventail d’avantages inattendus.
Honey Can Prevent Diabetes?
Yes, you are not hearing wrong: Honey can reduce blood sugar despite being roughly 80 percent sugar. In addition to lowering blood sugar, honey can boost immunity and slow the aging process. Recently, researchers have shown that honey has a wide range of unanticipated advantages. For example, diabetics who consume honey in moderation might significantly reduce their risk of developing heart disease and diabetes complications.
Miracle Herb Cinnamon Improves Memory and Learning Capacity
Cinnamon is a well-known aromatic spice commonly used in baking and delicacies, but a study published in Nutritional Neuroscience on Jan. 18 indicates its potential value for preventing memory loss and learning disabilities. This study suggests some good news for the middle-aged and elderly, since memory loss is inevitable as we age. Cinnamon is also an amazing herbal material.
In Social Security Spousal Benefits, Is Income Disparity OK?
Editor’s note: This is part two of a two-part series about how divorce and other circumstances can affect Social Security Social Security benefits and retirement income. Part one is The Impact of Social Security on Divorced Retirement Income. In my previous article, I covered the basics of Social Security for divorced individuals. We saw how a divorced spouse qualifies for their own benefit or 50% of their ex’s primary insurance amount (PIA) and what it means in practice.
The Impact of Social Security on Divorced Retirement Income
Editor’s note: This is part one of a two-part series about how divorce and other circumstances can affect Social Security benefits and retirement income. Part two explores the differences in retirement income for divorced spouses: Is a 35% Difference in Retirement Income Fair and Equitable? The complexities of Social Security retirement benefits make it a difficult topic for divorce settlement negotiations.
Habitual Tea Drinking Can Prevent Alzheimer’s Disease and Heart Disease
Drinking tea is a traditional custom in China and other Asian countries. However, tea culture has gained popularity in the United States in recent years due to its multiple health benefits. Tea is the most widely consumed beverage in the world next to water and can be found in almost 80 percent of all U.S. households, according to the Tea Association of America.
‘I Almost Died. It Was the Best Thing That Ever Happened to Me’
As the world responded to the spread of COVID, I thought: I'm in great shape. I'm only 44 and I'm strong. I'll be fine; let's just get it over with. On June 22, 2020, our entire extended family of 14 was getting ready to leave on a trip to Colorado. Before leaving, and although none of us had any symptoms, we did the responsible thing and went in for a COVID test. Surprisingly, although she was asymptomatic, my wife Stephanie's test came back positive.
Study: Men, Women Benefit From Exercise at Different Times of Day
Though the advantages of exercise are well known, for middle-aged and elderly people, exercise is an essential everyday activity. Physical immunity can decrease with age, leaving one more vulnerable to everything from simple colds to chronic diseases. Exercise helps strengthen immunity and prevent cardiovascular disease, diabetes, and other ailments. To reap the benefits of exercise, choosing the best time for various activities is important.
Aspirin Can Lower Risk of Heart Disease in Some Diabetic Patients
More than 65 percent of total mortality from diabetes is due to cardiovascular disease, including fatal atherothrombotic events such as acute myocardial infarction (heart attack), ischemic stroke (due to reduced blood flow and oxygen levels), critical ischemia of lower limbs, and sudden heart failure.
Moderate Sunlight Found to Prevent Dementia
You are probably exposed to sunlight on a daily basis and know of its health effects. But you may not know that too much or too little sunlight holds no health benefit. For example, a recent study found that sunlight helps prevent dementia—but only when exposure is moderate. Why is that? And how much is “moderate”?
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