Christa Müller on Muck Rack

Christa Müller

As seen in: Nature, Der Tagesspiegel, ACS Publications, Royal Society of Chemistry, Cell Press, Frankfurter Rundschau, Meedia, Absatzwirtschaft, NotiUlti, Stadt+Grün and
Chefredakteurin @aswonline
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Articles

A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 receptor - Nature Communications

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By Adam C Oken, Andreea Turcu, Jessica Nagel, Annette Nicke, Christa Müller, Antonios Kolocouris, Santiago Vazquez, Santiago Justel Vázquez, Franka G. Westermann
| Nature
Abstract The P2X7 receptor is an ATP-gated ion channel that activates inflammatory pathways involved in diseases such as cancer, atherosclerosis, and neurodegeneration. However, despite the potential benefits of blocking overactive signaling, no P2X7 receptor antagonists have been approved for clinical use. Understanding species-specific pharmacological effects of existing antagonists has been challenging, in part due to the dearth of molecular information on receptor orthologs.
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Heilungsprozesse im Kontext von Migration und Trauma: Solidarische Gärten, solidarische Ernte

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By Christa Müller
| Stadt+Grün
18.08.2025 - 09:00 von: Dipl.-Psych. Pauline Morley, Dr. Christa Müller Die Geschichte der urbanen Gemeinschaftsgärten ist eng mit der Einwanderung von Geflüchteten verknüpft. Es waren Frauen aus Bosnien, die in Unterkünften auf engstem Raum lebten und zur Untätigkeit verdammt waren. Was sie vor allem und schmerzlich vermissten, waren ihre großen Gemüsegärten.
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GPR17 - orphan G protein-coupled receptor with therapeutic potential

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By Michael Lewash, Evi Kostenis, Christa Müller
| Cell Press
Keywords agonists antagonists GPR17 G-protein-coupled receptor multiple sclerosis remyelination GPR17 – a promising drug target for multiple sclerosis and beyond GPR17 is a class A (rhodopsin-like), δ-branch GPCR (see Glossary).
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