Christopher Earley on Muck Rack

Christopher Earley

Boston
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Articles

Dopaminergic hypersensitivity of the opioid-responsive striatal–entopeduncular pathway in a rodent model of restless legs syndrome

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By William R. Rea, Cesar Quiroz, César Camacho Quiroz, William Sanchez, Ana M. Rule, Francisco Ciruela, Christopher Earley, Sergi Ferré, Marta Valle-León, Sandra Albornoz, Ning-Sheng Cai
| Nature Verified
Abstract We hypothesized that Restless Legs Syndrome (RLS) and the restlessness of opioid withdrawal share common neurobiological mechanisms based on the efficacy of μ-opioid receptor (MOR) agonists in RLS and the common RLS-like phenotype of patients with opioid withdrawal. We also hypothesized this involves an increased sensitivity of the striatal striosomal neurons that co-express MORs and dopamine D1 receptors (D1Rs) and release GABA in the internal segment of the globus pallidus (GPi).
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Seven things that catapulted my career

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By Christopher Earley
| Virginia Lawyers Weekly Verified
Over the past five years, I’ve implemented seven strategies that meaningfully moved the needle in my legal career. Each required time, effort and, in some cases, financial investment. None of the strategies was easy, but all were worth it. Not every lawyer needs to do all seven. Implementing even one or two can produce meaningful results. The first was writing a memoir.
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7 things I’ve done in the last 5 years that catapulted my career

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By Christopher Earley
| Massachusetts Lawyers Weekly Verified
“Most people overestimate what they can achieve in a year and underestimate what they can achieve in five years.” — Bill Gates Over the past five years, I’ve implemented seven strategies that meaningfully moved the needle in my legal career. Each required time, effort, and in some cases financial investment. None of the strategies was easy, but all were worth it. Not every lawyer needs to do all seven. Implementing even one or two can produce meaningful results. The first was writing a memoir.
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