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Chul Hoon

As seen in: Frontiers, PNAS
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Articles

Pharmacological chaperones mitigate noise-induced hearing loss by attenuating sustained PERK activation

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By Ji Won, Chul Hoon, Heon Yung, Hyeong Gi
| PNAS Verified
D. I. Nelson, R. Y. Nelson, M. Concha-Barrientos, M. Fingerhut, The global burden of occupational noise-induced hearing loss. Am. J. Ind. Med. 48, 446–458 (2005). T. N. Le, L. V. Straatman, J. Lea, B. Westerberg, Current insights in noise-induced hearing loss: A literature review of the underlying mechanism, pathophysiology, asymmetry, and management options. J. Otolaryngol. Head Neck Surg. 46, 41 (2017). S. Chadha, K. Kamenov, A. Cieza, The world report on hearing, 2021. Bull. World Health Organ. 99, 242A–242A (2021). J. D.
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Time-dependent biphasic alterations in brain metabolism following chronic ketamine exposure in mice

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By Chul Hoon
| Frontiers
Introduction Ketamine is a widely used anesthetic and NMDA (N-Methyl-D-Aspartate) receptor antagonist that has gained attention for its rapid antidepressant effects, particularly in treatment-resistant depression. However, in the context of repeated or prolonged administration, concerns about its long-term neurobiological consequences, especially addiction and metabolic disturbances, are growing (Alnefeesi et al., 2022; Strous et al., 2022).
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