Claudia Roberts

Abstract Ablative fractional carbon dioxide (AFCO2) laser therapy is used for treating pathological scarring. However, mechanisms underlying reduction in hypertrophic scarring are poorly understood. We investigated cellular mechanisms of AFCO2 laser therapy by performing single-cell RNA sequencing (scRNA-seq) on skin biopsies from burn survivors with hypertrophic scars before and after three sessions of AFCO2 therapy. Scar reduction was assessed subjectively and objectively.

One of the most researched topics in child development is what strategies are most effective in getting children to listen and behave better. Nearly every parent has or will experience the frustrating undertaking of managing temper tantrums, disobedience, and other behavioral challenges. As children age, the tools used to encourage positive behavior and conduct can also shift making it important for parents to stay informed and flexible in their parenting methods.