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Articles by Colm Cunningham
The neuroscience of delirium: a perfect storm for acute brain dysfunction
Abstract Delirium is a frequent and distressing neuropsychiatric syndrome characterized by acute disturbances of attention, awareness and cognition. Delirium emerges in response to diverse medical insults, particularly in hospitalized patients. Despite its high prevalence and association with accelerated cognitive decline, dementia and mortality, the neurobiology of delirium remains incompletely understood, and there are no treatments for delirium.
A new way to keep First Nations people with dementia connected to Country, community, family and culture
A decline in verbal skills is a source of grief for any person living with dementia. For First Nations peoples, the loss of speech brings the added pain of lost connection to Country, community, family and culture, which are so central to their health and well-being. Dementia is a serious emerging health issue for Indigenous people, who experience the disease at a rate between three to five times that of the general population, with onset at an earlier age.
When responsive and reactive meet organic? Treatment implications of language use in the era of #BanBPSD
EDITORIAL Mustafa Atee Corresponding Author matee@dementia.com.au orcid.org/0000-0002-0837-3245 The Dementia Centre, HammondCare Wembley, WA, Australia Curtin Medical School, Faculty of Health Sciences, Curtin University Bentley, WA, Australia Correspondence 17A/151 Herdsman Parade, Wembley, WA 6014, Australia, Email:matee@dementia.com.au Search for more papers by this author This article has been accepted for publication and undergone full peer review but has not been through the...
Characterising neuropsychiatric disorders in patients with COVID-19
We commend Aravinthan Varatharaj and colleagues for their study on neurological and neuropsychiatric complications of COVID-19, and we echo their comments on the importance of interdisciplinary work in the clinical neurosciences. However, we are concerned by their reliance on the vague term altered mental status and the use of the term encephalopathy without reference to delirium.
Language paradigms when behaviour changes with dementia: #BanBPSD
EDITORIAL Language paradigms when behaviour changes with dementia: #BanBPSD Stephen Macfarlane Corresponding Author E-mail address: smacfarlane@dementia.com.au https://orcid.org/0000-0003-1347-4945 Dementia Centre, HammondCare Alfred Psychiatry Research Centre, Faculty of Medicine, Nursing & Health Sciences, Monash University, Victoria, Australia Search for more papers by this author Henry Brodaty Dementia Centre for Research Collaboration, School of Psychiatry, University of New South Wales,...
Priming Microglia for Innate Immune Memory in the Brain
Highlights Microglia can adapt their phenotype depending on their history of inflammatory signal exposure, reflecting a status of immune memory. Such changes in microglial responses can significantly impact the progression of neurological disease in mouse models. The concept of microglial ‘priming’ originally described a permissive state facilitating an exacerbated inflammatory response when an acute inflammatory insult is superimposed onto an ongoing inflammatory process.
Reduce the burden of dementia now
Although Congress has allocated substantial funding to accelerate dementia research, nearly all attempts to find effective preventions and treatments for dementia have failed. Current dementia therapies offer little hope. They provide only modest clinical benefits and have limited impact on the unrelenting progression of disease.
Caring for people with dementia in A&E
Feature Previous Next Colm Cunningham Associate director of health and social care, The Dementia Services Development Centre, at the University of Stirling Katie McWilliam Strategic programme manager, Care for older people at NHS Lothian Colm Cunningham and katie Mcwilliam describe some simple steps to improve care for people with dementia in A&E Dementia affects about one person in 20 over the age of 65, and one in three over the age of 90 (Gow and Gilhooly 2003). Emergency Nurse. 14, 6, 12-16.
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