D. Dunbar Ivy

Highlights • Pediatric pulmonary hypertension subjects with a clinical worsening event had lower RA cF% at both baseline and 1-year follow-up. • Changes in RA cF% over time mirror changes in clinical risk of adverse events: subjects with high risk RA cF% at baseline who improved by 1-year had fewer events than those with persistently impaired RA cF% while subjects with low risk RA cF% at baseline who worsened by 1-year had more events than those with persistently preserved RA cF%.

To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Figure 1 Consort diagram demonstrating the patients evaluated for the current study and the final study cohort. Figure 2 Chest radiograph demonstrating bilateral ill-defined nodular opacities consistent with HAPE, in this case predominantly in the upper lobes. Figure 3 Elevation of symptom presentation in meters by type of HAPE and home elevation in meters.

To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Figure 1 Results of AVT. A, Change in mean PA pressure from baseline condition to after addition of vasodilator therapy in reactive and nonreactive participants. B, Change in PVRi from baseline condition to after addition of vasodilator therapy in reactive and nonreactive participants. Data are presented as median ± IQR. *P < .05.