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Articles by Dali Wang
Distinct metabolomic and proteomic signatures in Parkinson’s disease patients with REM sleep behavior disorder
Abstract Rapid eye movement sleep behavior disorder (RBD) is the most specific prodromal marker of Parkinson’s disease (PD), affecting 40–50% of PD patients. PD with RBD (RBD-PD) represents a clinically aggressive subtype characterized by more severe motor and nonmotor symptoms, prominent autonomic dysfunction, and accelerated disease progression; however, its underlying pathogenesis remains poorly understood.
SecY translocon chaperones protein folding during membrane protein insertion
Keywords protein translocation membrane protein insertion chaperone SecY channel Introduction Membrane proteins are involved in essentially every aspect of cellular processes. The biogenesis of membrane proteins is one of the key processes in maintaining cell functioning.
Supramolecular Polymers for Drug Delivery
Conflict of Interests The authors declare no conflict of interest. References 1 1a, , , Nat. Biomed. Eng. 2021, 5, 951–967; 1b, Science 1990, 249, 1527–1533; 1c, , Science 2004, 303, 1818–1822. , Nat. Rev. Drug Discovery 2003, 2, 347–360. 2 2a, , , , , , Adv. Mater. 2015, 27, 498–526; 2b, , Chem. Soc. Rev. 2017, 46, 6600–6620; 2c, , , Science 2012, 335, 813–817; 2d, , , , Chem. Rev. 2001, 101, 4071–4098; 2e, , , , , , , Science 1997, 276, 384–389; 2f, , , , , , , Prog. Polym. Sci.
Portable Software Environment for Ultrahigh-Resolution ELM Development on GPUs
1. Introduction Advanced Earth system models (ESM) are crucial for providing insights into climate variations and enhancing our comprehension of the interplay between natural and human systems and the Earth’s climate. The Energy Exascale Earth System Model (E3SM) is a fully integrated ESM that employs code tailored for the US Department of Energy’s (DOE) supercomputers to tackle the most pressing Earth system science issues [1].
Photoelectrocatalyzed Alkylation of Phosphonites by Direct Decarboxylative C(sp3)‐P Coupling
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Response to ‘Promoting diabetic foot wound healing through antibiotic bone cement: Focus on ROCK1 protein expression’
Dear Editor, Thank you very much for your letter. It is an honour to have the opportunity to exchange views and methods with you, aiming for better treatment outcomes for patients with diabetic foot ulcers.
Script-Based GPU-Ready ELM Development for Continuous Code Integration
1. Introduction State-of-the-art Earth system models (ESM) provide critical information on climate change. There are several fully-coupled ESMs, including the Energy Exascale Earth System Model (E3SM) that uses code optimized for the US Department of Energy’s (DOE) advanced computers [1] . The E3SM Land Model (ELM) is an integral part of the E3SM framework, simulating the interactions between terrestrial land surfaces and other Earth system components.
Antibiotic bone cement accelerates diabetic foot wound healing: Elucidating the role of ROCK1 protein expression
1 INTRODUCTION Diabetic foot ulcers present a major clinical challenge, with less than 70% healing1 and one-third leading to lower limb amputation.2 The condition has reached epidemic proportions3 and imposes significant clinical and quality-of-life burdens.
METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy
INTRODUCTION Diabetic kidney disease (DKD) is a microvascular complication of diabetes1. DKD is characterized by the increased formation of extracellular matrix and the disappearance of foot process, which eventually leads to increased urinary protein and a decreased estimated glomerular filtration rate2. Previous studies have shown that DKD is the result of the interaction of hemodynamic disorders and metabolic abnormalities3.
Effects of Erythromycin on Nereis succinea and the Intestinal Microbiome across Different Salinity Levels
Download Hi-Res ImageDownload to MS-PowerPointCite This:Environ. Sci. Technol. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
International Congress on Environmental Modelling and Software: Early experience in ultra-scale E3SM land model development on SUMMIT
Home > Engineering > Civil and Environmental Engineering > iEMSs Conference > 2020 > STREAM-C > 8 Keywords E3SM Land model, Exascale Computing, OpenACC, SUMMIT, Functional Unit Testing DOWNLOADS COinS Sep 15th, 3:40 PM Sep 15th, 4:00 PM Early experience in ultra-scale E3SM land model development on SUMMIT The Energy Exascale Earth System Model (E3SM) is a computationally advanced coupled climate-energy model investigating the challenges posed by the interactions of weather-climate scale...
Distinct effects of nano-polystyrene, erythromycin and their mixtures on composition and metabolic profile of intestinal microbiota in Nereis succinea
Distinct effects of nano-polystyrene, erythromycin and their mixtures on composition and metabolic profile of intestinal microbiota in Nereis succinea Dali Wang, Yuheng Zhong, Qi Ding, Xiaofeng Han, Kai Chen, Bo Pan and Jing You Abstract Nanoplastics (NPs) and antibiotics are emerging contaminants that co-occur ubiquitously in coastal environment and pose mixture risk to ecosystems.
Drug-Grafted DNA for Cancer Therapy
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Di-CNN: Domain-Knowledge-Informed Convolutional Neural Network for Manufacturing Quality Prediction
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Value of contrast-enhanced ultrasound in the differential diagnosis of ureteral tuberculosis from ureteral malignant tumour in women | Epidemiology & Infection | Cambridge Core
Hostname: page-component-789cc574b8-jngkm Total loading time: 0 Render date: 2023-04-11T13:06:27.669Z Has data issue: false Feature Flags: { "useRatesEcommerce": false } hasContentIssue false Published online by Cambridge University Press: 15 March 2023 Wenzhi Zhang [Opens in a new window] , Show author details Rights & Permissions[Opens in a new window] Abstract This study aimed to evaluate the contrast-enhanced ultrasound (CEUS) features of ureteral tuberculosis (UTB) and ureteral malignant...
Mutual effects of microplastics and microbes: tiny things have big impacts
• None Lost at sea: where is all the plastic? 304(5672), 838 ( ).Medline, CAS • None . Effects of accelerated aging on characteristics, leaching, and toxicity of commercial lead chromate pigmented microplastics . 257, 113475 ( ).Medline, CAS • None Microplastic bacterial communities in the Bay of Brest: influence of polymer type and size .
Electric field modulated valley- and spin-dependent electron retroreflection and Klein tunneling in a tilted $n\text{\ensuremath{-}}p\text{\ensuremath{-}}n$ junction of monolayer $1{T}^{\ensuremath{'}}\text{\ensuremath{-}}{\mathrm{MoS}}_{2}$
Abstract We study the electronic transport properties in a tilted n−p−n junction of monolayer 1T′−MoS2 under a vertical electric field. The analytical derivations and numerical results show that, since the spin degeneracy of the anisotropic bands of monolayer 1T′−MoS2 is lifted by the electric field Ez, electrically tunable valley- and spin-dependent electron retroreflection occurs in the tilted n−p−n junction.
A New Perspective of Post-Weld Baking Effect on Al-Steel Resistance Spot Weld Properties through Machine Learning and Finite Element Modeling
Abstract : The root cause of post-weld baking on the mechanical performance of Al-steel dissimilar resistance spot welds (RSWs) has been determined by machine learning (ML) and finite element modeling (FEM) in this study. A deep neural network (DNN) model was constructed to associate the spot weld performance with the joint attributes, stacking materials, and other conditions, using a comprehensive experimental dataset.
International Congress on Environmental Modelling and Software: Early experience in ultra-scale E3SM land model development on SUMMIT
Sep 15th, 3:40 PM Sep 15th, 4:00 PM Early experience in ultra-scale E3SM land model development on SUMMIT The Energy Exascale Earth System Model (E3SM) is a computationally advanced coupled climate-energy model investigating the challenges posed by the interactions of weather-climate scale variability with energy and related sectors. E3SM contains a community land model for understanding how natural and human changes in terrestrial land surfaces will affect the climate.
Cellular Response of Freshwater Algae to Halloysite Nanotubes: Alteration of Oxidative Stress and Membrane Function
Cellular Response of Freshwater Algae to Halloysite Nanotubes: Alteration of Oxidative Stress and Membrane Function Xiaochen Huang, Yichao Huang, Dali Wang, Mingxian Liu, Jing Li and Da Chen Abstract Halloysite nanotubes (HNTs) are a low-cost clay nanomaterial that has received an increasing amount of attention for applications in various fields. The use of HNTs-containing products inevitably leads to their release into aquatic environments.
Spherical Nucleic Acids for Topical Treatment of Hyperpigmentation
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc.
Gut Microbial Profiles in Nereis succinea and Their Contribution to the Degradation of Organic Pollutants
Gut microbiota of wildlife are usually exposed to and involved in degrading environmental pollutants, yet their biodegrading capacity remains largely unexplored. Here, we analyzed gut microbial profiles of a marine benthic polychaete, Nereis succinea, and elaborated the capacity of gut microbiota in degrading various organic pollutants, including polycyclic aromatic hydrocarbons, pesticides, phenols, and synthetic musks.
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