Dana Mamriev

Keywords nuclear pore complexes nucleoporin CCR4-CNOT translation degradation proteostasis Research topic(s) CP: Cell biology CP: Molecular biology Introduction Nuclear pore complexes (NPCs) are large protein channels that connect the nucleus with the cytoplasm and mediate the exchange of molecules between these compartments.

Bcl-2 Protein Levels Are Downregulated by the Ubiquitin Proteasome System during Apoptosis ARTS Is Required for Downregulation of Bcl-2 Levels in the Cytosol ARTS Is Required for the Formation of a Ternary Complex with Bcl-2 and XIAP ARTS Interacts with the BH3 Domain of Bcl-2 XIAP Serves as an E3-Ligase for Bcl-2 ARTS Is Required for Ubiquitin Proteasome System-Mediated Degradation of Bcl-2 by XIAP Lysine 17 Is the Main Ubiquitin Acceptor in Bcl-2 Bcl-2 Protein Levels Are Downregulated by...