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Daniel Barnes

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Articles

Natural menopause, menarche and breast cancer risk in BRCA1 and BRCA2 pathogenic variant carriers: a Mendelian randomization analysis

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By Nasim Mavaddat, Daniel Barnes, Kyriaki Michailidou, Emily Zhao, Debra Frost, Goska Leslie, Joe Dennis, Qin Wang, Manjeet K. Bolla, D. Gareth Evans, Marc Tischkowitz, Deborah Thompson, Antonis C Antoniou, Douglas F. Easton
| Nature Verified
Abstract The influence of age at menarche (AAM) and age at natural menopause (ANM) on breast cancer (BC) risk in BRCA1 and BRCA2 germline pathogenic variant (PV) carriers is uncertain. Observational studies are prone to bias and have limited statistical power. Mendelian randomization (MR) minimises bias and may be used to examine causal effects. Two-sample and age-specific MR analyses for BC were performed.
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"Genome-Wide Association Study of 398,238 Women Unveils Seven Loci Asso" by Daniel R Barnes, Jonathan P Tyrer et al.

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By Daniel Barnes
| Texas Medical Center
NPJ Genome Medicine 10.1038/s41525-025-00529-w Post-print Cancer genetics, Ovarian cancer, Cancer epidemiology, Cancer genetics, Ovarian cancer yes Barnes, Daniel R; Tyrer, Jonathan P; Dennis, Joe; et al., "Genome-Wide Association Study of 398,238 Women Unveils Seven Loci Associated With High-Grade Serous Ovarian Cancer" (2025). Faculty, Staff and Student Publications. 5297. https://digitalcommons.library.tmc.edu/uthgsbs_docs/5297
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Judge blocks Trump administration from terminating DEI-related grants

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By Daniel Barnes, Nnamdi Egwuonwu Verified
| WRC-TV (Washington, DC) Verified
AP Photo/Ben Curtis A federal judge in Maryland on Friday blocked the Trump administration from terminating federal grants and contracts related to DEI as called for in executive orders signed by President Donald Trump. "Plaintiffs have amply established a likelihood that they will succeed in proving that the Termination Provision invites arbitrary and discriminatory enforcement over billions of dollars in government funding," U.S. District Judge Adam Abelson ruled.
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