Daniel He
As seen in:
Medium,
Nature,
PLOS ONE,
The Epoch Times,
Cell Press,
Journal of Virology,
Michelin,
Michelin Guide,
Daily Northwestern,
Wevolver
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Articles by Daniel He
PAWR augments anti-RNA viral innate immunity by promoting the PIM2-XBP1s-RIG-I signaling axis
Abstract PRKC Apoptosis WT1 Regulator (PAWR) has been implicated in tumorigenesis. However, its role in antiviral innate immunity remains unexplored. Here, we demonstrate that PAWR transcriptionally upregulates RIG-I expression through the transcription factor X-box binding protein 1 (XBP1). Mechanistically, PAWR potentiates the ATF6/IRE1-XBP1 pathway to upregulate spliced form XBP1 (XBP1s) and simultaneously promotes PIM2-mediated phosphorylation of XBP1s at Ser68.
Visit These Unique Restaurants You Can Only Find in California
When it comes to food, there’s something that makes California special. Maybe it’s the incredibly fresh produce, the seasonality of ingredients, the farm-to-table ethos that originated in the state. “From Napa wines and Central Valley fruits to seafood from the California coast, chefs have access to produce that is rare or unavailable in other states,” says JuMi Pitiwartarlai, chef and co-owner of Sovereign in San Diego.
If determinism is true, do we have free will and moral responsibility?
If determinism is true, do we have free will and moral responsibility? When we reflect on our past actions — “Was I wrong to say that?” or “Should I have treated that person differently?” — we typically assume we made these choices, or that there were alternative options, and are responsible for our decisions. This belief in free will shapes how we judge behaviour and define moral responsibility.
Emergency Mission 2024: DEEP Robotics' Robot Dog Scouts for Fire and Explosion Hazards
Recently, Zhejiang Province in east China carried out a comprehensive emergency response drill "Emergency Mission 2024" to strengthen its capabilities in responding to natural disasters. During this drill, a certain fire brigade collaborated with DEEP Robotics to provide a "quadruped robot hazard rescue solution." The robot dog, in coordination with drones, successfully completed the task of scouting for chemical explosion hazards. Quadruped robots possess superior terrain adaptability.
DEEP Robotics Lands Applications in Singapore and South Korea! Will Quadruped Robots Experience an Application Boom?
In Singapore, DEEP Robotics, in collaboration with its official partner EGP, is participating in the AMR SPPG Tunnel Project of the Singapore Powergrid (SPPG). This project utilizes quadruped robots for power tunnel inspections and integrates related detection systems to provide early warnings for emergencies. This marks the first time domestically-produced quadruped robots have been involved in overseas power industry applications.
DEEP Robotics launches X30 quadruped robot to meet varied industry needs
DEEP Robotics Company, a global pioneer in the development and industrial application of quadrupedal robots, announced the launch of its X30 quadruped robot, a flagship product designed to meet core industry needs in multiple fields, including inspection of power stations, factories, pipeline corridors, emergency rescue, fire detection, scientific research and more.
Northwestern women’s tennis falls in narrow rivalry match to Illinois
Daily file photo by Charlotte Che Graduate student Ema Lazic prepares to serve the ball. Lazic was unable to rally in a three-set singles loss during No. 39 Northwestern’s 4-3 defeat to No. 47 Illinois on Sunday. Daniel He and Alex Cervantes April 20, 2022 Women’s Tennis No. 39 Northwestern suffered a close upset loss to in-state rival No. 47 Illinois on Sunday, fighting hard to a bitter 3-4 end.
DDIT3 Targets Innate Immunity via the DDIT3-OTUD1-MAVS Pathway To Promote Bovine Viral Diarrhea Virus Replication
Virus-Cell Interactions Song Wang, Peili Hou, Wei Pan, Wenqi He, Daniel Chang He, Hongmei Wang, Hongbin He Rozanne M. Sandri-Goldin, Editor DOI: 10.1128/JVI.02351-20 ABSTRACT DNA damage-inducible transcript 3 (DDIT3) plays important roles in endoplasmic reticulum (ER) stress-induced apoptosis and autophagy, but its role in innate immunity is not clear.
DDIT3 targets innate immunity via the DDIT3-OTUD1-MAVS pathway to promote BVDV replication
Virus-Cell Interactions Song Wang, Peili Hou, Wei Pan, Wenqi He, Daniel Chang He, Hongmei Wang, Hongbin He DOI: 10.1128/JVI.02351-20 ABSTRACT DNA damage inducible transcript 3 (DDIT3) plays important roles in ER stress-induced apoptosis and autophagy, but its role in innate immunity is not clear.
Cholinergic synapse pathway gene polymorphisms associated with allergen-induced late asthmatic responses
Ashwini Rajasekaran, Daniel He, Alice Yue, Amrit Singh, Casey P. Shannon, J. Mark FitzGerald, Louis-Philippe Boulet, Paul M. O'Byrne, Gail M. Gauvreau, Scott J.
Dangerous Wave Sweeps Elderly Couple Away
The sea can be unpredictable at times, and strike when we least expect it. Last week, an elderly couple was walking along a path on a beach, in Portsall, France. As soon as the couple started to walk down to the shoreline, a rogue wave came blasting towards them. By the time they tried to back away, it was already too late. Video footage captured the rogue wave crashing in on the septuagenarians while a handicapped man filmed what happened next.
Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis
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By Daniel He, Luis Luna-Zurita, Christian U. Stirnimann, Sean Thomas, Sean Thomas Verified, Andras Nagy Verified, Katherine S. Pollard, Eric Small, Christoph Müller, Luis Luna-Zurita, Sebastian Glatt, Bogac L. Kaynak, Christian U. Stirnimann, Sebastian Glatt, Bogac L. Kaynak, Florence Baudin, Maria Mileikovsky, Alisha K. Holloway
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Cell Press
Verified
First Flower Blooms in Space, Key to Living on Mars
Astronaut Scott Kelly has tweeted a photo of the first flower to successfully bloom in space. But it wasn’t easy to get to this point. It all started with a project initiative named the Veggie Plant Growth System, or “Veggie,” for short. Developed by an aerospace company, Veggie was activated in early May of 2014. The first crop, red romaine lettuce, was stimulated for growth (or ready for action). However, the project faced some issues.
Cat Resembling 'Star Wars' Actor Adam Driver Is Newest Viral Kitty
A picture posted by Twitter user Marci Robin (@MarciRobin) showed a cat with an eerie resemblance to “Star Wars: The Force Awakens” star Adam Driver, who played the evil Kylo Ren. The tweet has since gone viral. The cat, pictured resting on a shelf, was found at the Monmouth County Adoption Center in Eatontown, New Jersey. The kitty named Corey has since been adopted by Emily McCombs, an editor at Elite Daily.
Easter the Turkey Is More Than Just a Pet
A turkey named Easter surprised nearby passengers when it was noticed sitting on a seat on an airplane. Easter was travelling with her owner, Jodie Smalley, to visit her relatives for Christmas. The two were travelling from Seattle, WA on a Delta flight en route to Salt Lake City, Utah. After landing, Smalley pushed the bird in a wheelchair, on their way out of the airport. Easter clearly made a big impact on his journey. The flight attendants and airport staff were all excited to witness the sight.
Boy Gets Girl With 148-Day Proposal
A man spent 148 days preparing to propose to his girlfriend on Christmas. Ray Smith, took a selfie with his now-fiancée, Claire Bramley, everyday starting on July 31 of last year. Smith uploaded a Youtube video titled, “My unusual 148 day wedding proposal to claire,” showing all the photos from the last few months. “It was hardwork not getting caught I took numerous photos incase she asked to see them and i’d showed her which ones I wanted, ” he wrote in the comments section.
Folk Singer to Go to Syria to Bring Peace to ISIS
Musician and filmmaker James Twyman is planning to hold a peace concert in ISIS-controlled Syria. Known as the ‘Peace Troubador,’ Twyman believes he can pacify the terrorists with his musical-prayer concert. The concert will be held on Jan. 31, in an Israel-occupied Syrian-Druze village known as Majdal Shams. Twyman will be joined by Muslim, Christian, and Jewish spiritual peace leaders as well as by millions in prayer around the world.
Here's the Awesome Alan Rickman Tribute Cartoon From The New Yorker
The New Yorker posted a cartoon in tribute to the legacy of the late Alan Rickman, who passed away on Thursday from pancreatic cancer at the age of 69. Rickman, famous for portraying the main antagonist in a number of films, starred in the Harry Potter movies, as well as in Die Hard series. In both roles he portrayed a complicated but intriguingly-likable villain. In the cartoon drawn by Dr. Benjamin Schwartz, Harry Potter and John McClane, have a drink together.
Viral Video Shows Unique 'Cookie" Tribute to David Bowie
Tastemade, a video sharing network for food and travel, posted a painted cookie design in honor of the late singer David Bowie. The charming footage, which has gone viral, shows a cookie getting decorated and colored to Bowie’s Ziggy Stardust persona. “I don’t know where I’m going from here, but I promise it won’t be boring,” quoted Tastemade from a line from Bowie on his 50th birthday concert at Madison Square Garden. The legendary singer passed away last Sunday from liver cancer.
Anglers Warn Tourists, Catch Sharks to Prove It
A father and son duo, Anthony and Chris Micallef, have been catching sharks at tourist hotspots to warn people of the dangers lurking in the water. However, it doesn’t seems like their efforts are having much of an impact. The two Port Macquarie shark hunters were fishing for sharks at a popular tourist spot called Hastings Rivers, in New South Wales, Australia. Many tourists go there to swim and water-ski.
David Bowie's Wife, Iman Shares Last Moments Before Husband's Death
Iman Abdulmajid, wife of David Bowie shared with the world some emotional thoughts in the final days leading up to her husband’s death. Married to Bowie for 23 years, Iman posted a series of pictures, quotes, and captions reflecting on the rock star’s stardom, life, and legacy. Out of the many posts she tweeted, she posted this one before the death of Bowie and it really hit home hard. This one, like many others was captioned with a single ‘Rise’.
Olly The Cat is Back on UK Supermarket Shelves
The supermarket cat Olly has returned to lurk the aisles after being removed a few months ago due to being a “health and safety risk,” according to the Telegraph. First spotted last November at a Sainsbury’s store in Brockley, a district in South London, Olly has become a “Top Internet Cat” with a growing fan base. As a frequent visitor, Olly has been removed a few times in the past from the store. But this time, he’s come back to show who’s boss.
Rapper Arrested After Withdrawing $200K from Account, Reports Say
Just moments after withdrawing $200,000 cash from a Wells Fargo Bank outside Atlanta, Georgia, rapper Blac Youngsta, was stopped by police and handcuffed. The incident was captured on camera, and it was posted on his Instagram. The 25-year old rapper was touring with his entourage, and had briefly made a pit stop for some cash on their way to pick up a new Mercedes-Maybach S600. The confused bank believed Youngsta to have been a wanted check fraudster.
Visible Light From a Black Hole Has Been Detected for the First Time Ever
It’s impossible see directly into a black hole and gaze inside its event horizon. But in some circumstances, when a black hole devours nearby star material, it creates a spectacle that can be viewed as enormous radiation. Scientists are able to observe this as light coming from the black hole just before it disappears into the black hole using high frequency gamma, or X-ray, telescopes.
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