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Articles by Daniel Weghuber
Effect of weight loss interventions on liver-related health in children and adolescents with obesity: a systematic review and meta-analyses Original
Abstract Metabolically-dysfunction-associated steatotic liver disease is today rising in prevalence among children and adolescents with obesity. The present Systematic Review and Meta-analysis explores the effect of weight loss interventions, depending on their modality (lifestyle, bariatric surgery or anti-obesity medication) on circulating, imagery-related and histology-related liver parameters in children and adolescents with obesity (aged 5–18 years).
Obesity Management Pharmacotherapies and Lifestyle Treatment for Pediatric Obesity Management : A Systematic Review and Network Meta-Analysis
Obesity Management Pharmacotherapies and Lifestyle Treatment for Pediatric Obesity Management: A Systematic Review and Network Meta-Analysis Key Points Question What is the comparative effectiveness of pharmacotherapies, structured lifestyle treatments, and their combinations for weight management in children and adolescents living with obesity?
Role of Hydrogen Sulfide in Inflammatory Bowel Disease
Abstract : Hydrogen sulfide (H2S), originally known as toxic gas, has now attracted attention as one of the gasotransmitters involved in many reactions in the human body. H2S has been assumed to play a role in the pathogenesis of many chronic diseases, of which the exact pathogenesis remains unknown. One of them is inflammatory bowel disease (IBD), a chronic intestinal disease subclassified as Crohn’s disease (CD) and ulcerative colitis (UC).
Semaglutide treatment for obesity in teenagers: a plain language summary of the STEP TEENS research study
Journal of Comparative Effectiveness ResearchAhead of Print Plain Language Summary of PublicationOpen Access Abstract What is this summary about? This is a plain language summary of the STEP TEENS research study, which was originally published in the New England Journal of Medicine. As more teenagers are living with obesity than ever before, researchers are searching for new treatments.
Once-Weekly Semaglutide in Adolescents with Obesity
Article Figures/Media Metrics Related Articles Abstract Background A once-weekly, 2.4-mg dose of subcutaneous semaglutide, a glucagon-like peptide-1 receptor agonist, is used to treat obesity in adults, but assessment of the drug in adolescents has been lacking.
Does the severity of obesity influence bone density, geometry and strength in adolescents?
ORIGINAL RESEARCH Valérie Julian, Corresponding Author vjulian@chu-clermontferrand.fr orcid.org/0000-0002-0045-1763 Department of Sport Medicine and Functional Explorations, University Teaching Hospital of Clermont-Ferrand, Diet and Musculoskeletal Health Team, CRNH, INRA, University of Clermont Auvergne, Clermont-Ferrand, France Department of Pediatrics, Paracelsus Medical School, Salzburg, Austria Correspondence Valérie Julian, Department of Sport Medicine and Functional Explorations,...
Elevated transaminases potentiate the risk for emerging dysglycemia in children with overweight and obesity
SHORT COMMUNICATION Florian Koutny, orcid.org/0000-0002-9446-2710 Department of Pediatrics, Paracelsus Medical University, Salzburg, Austria Obesity Research Unit, Paracelsus Medical University, Salzburg, Austria Search for more papers by this author Robert Stein, orcid.org/0000-0003-0896-9943 University of Leipzig, Medical Faculty, University Hospital for Children and Adolescents, Center for Pediatric Research, Leipzig, Germany Helmholtz Institute for Metabolic, Obesity and Vascular Research...
Prevalence of prediabetes and type 2 diabetes in children with obesity and increased transaminases in European German‐speaking countries. Analysis of the APV initiative
Summary Background Non‐alcoholic fatty liver disease (NAFLD), prediabetes and type 2 diabetes mellitus are known to be closely linked with obesity as early as during childhood. Objectives The study aimed to determine the prevalence of prediabetes and T2DM in children with obesity with or without increased transaminases. Methods Data from the observational multicentre (n = 51), cross‐sectional Adipositas Patienten Verlaufsbeobachtung registry were analyzed.
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