David Sinclair
- Marketing Coordinator, ReMax Prime Properties
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Managing Editor of The Pilot newspaper. Big NC State Wolfpack and Carolina Hurricanes fan.
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Articles by David Sinclair
Ageing should be a development priority
David Sinclair, ILC Chief Executive, argues that population ageing is one of the defining development challenges of our era – and that the world’s finance ministers are still not treating it with the urgency it demands.
No such thing as a silver economy – Asia’s longevity dividend
David Sinclair, ILC Chief Executive, argues that there is no such thing as a silver economy – just an economy that is increasingly dominated by people in their fifties, sixties and beyond, and that most investors and businesses have not yet adapted to that reality.
ILC in Bangkok: Do the World’s Finance Ministers care about ageing?
David Sinclair, ILC Chief Executive, argues that population ageing is no longer a rich-world story – and that the world’s finance ministers have not yet caught up with that reality. With the UK’s G20 Finance Ministers meeting in Edinburgh in July 2027, Sinclair argues the window to act is open – but narrowing faster than most governments yet appreciate.
Who gets France’s demographic dividend?
As French students take to the streets over conditions in their schools, ILC Chief Executive David Sinclair argues the real story is a demographic one. Falling pupil numbers are being used as justification for cuts rather than investment; pension spending consuming 13–14% of GDP is crowding out fiscal space for education; and the teaching workforce is itself ageing, with a retirement wave building over the next decade.
Jab well done – why the government’s tax change on flu vaccination should spark more policy change to support employer investment in health
David Sinclair highlights compelling new evidence of the importance of influenza vaccination and urges the government to do more to support employers to invest in prevention. It’s that time of year. I had my flu jab this week. At Tesco. It took about ten minutes and I picked up a meal deal on the way out. For years, the rules around employer-funded flu vaccination were a little absurd. Employers could support staff in getting jabbed – but only in certain ways.
Research Impact Collaboration Hub
I’ve just dropped my daughter back at the University of Warwick for her second year. Around 12,000 days ago, I arrived at the University of Hull as a fresher. I’d signed up for British Politics and Legislative Studies, a course that included a year working in Parliament. It was designed to produce lobbyists. And the kind of geek who knows that, until 1998, an MP raising a point of order during a vote had to put on a hat.
Effective prevention vs the online influencers
What does medical progress actually mean? This week’s Geneva Association Health and Demography Conference in London grappled with that question. The “wellness industrial complex” sells new digital monitoring devices and testing direct to the consumer. Meanwhile the basics of prevention are often right in front of us but underused and valued. OECD data shows health systems spend just 3% of their budgets on prevention.
Quality might be the key to unlocking the longevity dividend
Cheap has become the default setting of the global economy, writes David Sinclair – but Ed Conway’s new book on trade, and a throwaway line about sourdough, suggest older consumers might be exactly who could change that. If we’ve got enough crap, then rebuilding demand as we age may depend less on persuading people to spend and more on giving them something worth buying.
Expert on tap, not expert on top
With the new Prime Minister staking his reputation on giving power back to places, last night Professor Kate Ardern brought a practitioner’s account of what happens when you hand power back to communities. Kate delivered the third Greengross Lecture in Westminster, making a solid case for “Expert on tap rather than expert on top.” Kate served as Director of Public Health for Wigan between 2008 and 2022.
活到159岁：一场新的寿命革命，还是富人的幻觉？
过去，我们喜欢用“长命百岁”来祝福亲朋好友。 确实在人类漫长的发展历程里，活到100岁，已经是人们对于生命长度最美好的想象。 但放在今天，百岁人生是不是有点保守了？癌症疫苗已经出现，基因编辑过的猪肾可以移植进人体，AI开始从影像和血液蛋白中寻找疾病尚未发生的信号，一次注射修改慢性病相关基因的疗法也进入了人体试验。医学领域正在发生很重要的变化，过去主要是在身体出现问题后治病，今天则开始提前发现、清除、修补、替换和编辑。 我们对寿命的想象也在不断的拓宽，100岁不再像一道遥不可及的天花板，人们已经开始讨论活到120岁，甚至150岁。 而且那些真正激进的人，已经把目标写出来了。哈佛大学遗传学教授David Sinclair曾公开说，第一位活到150岁的人可能已经出生；企业家兼未来学家Peter Diamandis专门做过一期《活到156岁》的播客；科技富豪Bryan Johnson把自己变成一座24小时运行的人体实验室，口号干脆就是“Don’t Die”；Ray...
Healthy Ageing in Asia Pacific Economies
Writing from Dalian – a city of seven and a half million on China’s northeastern coast, where one in four residents are already over 60 – David Sinclair argues that healthy ageing is no longer just a health policy, it is a workforce policy. Dalian built its prosperity on human skill: language, software, back-office finance. That workforce is now shrinking, and no industrial robot replaces what made it. Prevention is the underused lever.
Frank Beard was the enigma at the heart of ZZ Top
Frank Beard, who has died at the age of 77 , spent much of his life sitting slightly apart from the mythology of ZZ Top .
Frank Beard was the enigma at the heart of ZZ Top. "I never wanted to quit ZZ Top. And I never wanted to get fired"
ZZ Top’s Frank Beard posing for a photograph in the 1980s. Frank Beard, who has died at the age of 77, spent much of his life sitting slightly apart from the mythology of ZZ Top.
Does cocaine have an age problem?
Cocaine is still mainly a young person’s problem, writes David Sinclair. But the rate at which it is becoming an older person’s problem is accelerating sharply – and the treatment system, as we found when we looked at alcohol a decade ago, is not ready for it. Earlier in the year I picked up a fascinating blog (via Marie Le Conte) about cocaine. “Ask anyone who runs a licensed establishment and either they’ll tell you that coke’s become a bit of a nightmare or they’re lying.
"I wanted to get Jeff Beck in the band. Then I wanted to get Keith Moon. I went for the big time." George Thorogood is at peace with not being Bob Seger or Steve Miller
Back when you started out in those early bar gigs in Delaware, what did a great night feel like? A great night was when nobody got hurt. That was our motive when we got into playing those barroom places. People drink a lot, they get excited, sometimes they take it too far. There’s a jealous husband or boyfriend. It could get rough. It’s better now. I like it better now. Was there a moment early on when you realised you had something that could last? The first time we played together.
The value of advice and the £47,000 answer
I remember a meeting with a senior Conservative MP about fifteen years ago. The Retail Distribution Review was being implemented and we had concerns about how to ensure that the new regulations would provide a platform to improve access to financial advice and guidance, rather than limit it to those willing to pay. We met a sceptical audience. The politician wasn’t convinced that advice worked and said he himself wouldn’t use an adviser.
Find a venue, find your people: what running events in more than 20 countries has taught us
In theory, running an event anywhere in the world comes down to two things Finding a venue Identifying the people you want in the room That is not far off. ILC has run events in more than 20 countries, from Romania and Germany, to Japan, China, Australia, Israel, Taiwan, the USA, Switzerland and the UAE. We’ve held residential events in France and high-level meetings alongside G7 and G20 summits.
More of us are saving. Not enough of us are saving enough.
New government data shows more of us are saving into workplace pensions than ever before. But opt-out rates have nearly doubled, women face a retirement income gap of thousands of pounds a year, and millions of workers are still outside the system entirely. David Sinclair, Chief Executive of the International Longevity Centre, crunches the numbers – and asks whether we have built a nation of pension savers without yet building a system that will actually see us through.
Pop the cap - ILCUK
This summer the BBC’s long-wave signal fell silent after nearly 92 years. The last GAME stores closed their doors. And GTA VI went on sale without a physical disc. A new Prime Minister arrived in Downing Street promising a “circuit breaker” moment for British politics. David Sinclair, Chief Executive of the International Longevity Centre, explores what these shifts tell us about our relationship with change – and why the absence of a plan, more than change itself, is what should concern us most.
"We were playing to capacity crowds, six or seven nights a week, everywhere we went. So we figured something was about to happen." The story of 1966, the year that built rock
“There was an underground feeling in the air,” John Mayall says of the period just before the Beano Album came out on July 22. “The people in the clubs were flocking to see us, regardless of what was happening in the record business or the pop charts. We were playing to capacity crowds, six or seven nights a week, everywhere we went. So we figured something was about to happen.” The electric guitar has always been part of the British pop dream.
ILC is a Living Pension Employer
ILC is a small charity with a tight budget and no core income. And we’ve just become a Living Pension accredited employer (we’ve been a living wage employer for many years). When I started at ILC a long time ago we didn’t even offer a pension. We set one up just before auto enrolment. But we were contributing at the minimum level. Five years ago, ILC’s employer pension contributions sat at around 4% of total salary costs. Today they’re at 7% – everyone in the team is contributing into their pension.
"We were playing to capacity crowds, six or seven nights a week, everywhere we went. So we figured something was about to happen." The story of 1966, the year that built rock
1965 Classic Rock Hit, Written by an 18-Year-Old, Was Rejected by Record Label Before Topping the Charts It goes without saying that there were plenty of teenagers in the '60s who worshipped the Beatles and dreamed of having their own music careers...but …
Running the numbers
David Sinclair explores what parkrun’s age data tells us about physical activity, ageing and volunteering. I run parkrun. Badly, and inconsistently – but I enjoy it. I’ve done 356 of them, mostly at Bognor Regis, over more than a decade. I’ve watched my times get slower and slower, then – more recently – start to come back. I’ve wanted to understand the relationship between age and participation for a long time. AI has allowed me to do a bit of analysis that in the past it would have been beyond me.
Guest Blog: Why are women living over a quarter of their lives in poor health?
We are living longer. But for too many of us – and particularly for women – those extra years are not healthy ones. New analysis from the Government Actuary’s Department highlights that on average, women now spend around 22 of their 83 years in poor health, compared to 18 out of 79 years for men. In the most deprived areas, that figure rises to over 30 years.
全球首例人体内细胞重编程抗衰老疗法开始临床试验，治疗青光眼
一种声称能让人体细胞“返老还童”的疗法，不久前刚完成了首例患者给药。这也是第一次有人尝试使用这种技术，在人体内直接重编程细胞，诱导衰老细胞恢复年轻状态。 当地时间6月9日，美国生物科技公司Life Biosciences宣布，首次接受治疗的是青光眼患者，将评估“ER-100”疗法的安全性和耐受性，包含受试者视觉功能恢复情况。 ER-100是一种极具想象力的创新基因疗法，它通过激活3个基因，从而改造衰老细胞，让它们恢复年轻时的功能。研究人员还设计了一个开关——多西环素。如果停止服用这种抗生素，“激活年轻的程序”就会关闭。 “如果能安全地应用于人体，基因重编程技术将具有巨大的潜力。”华盛顿大学健康老龄化与长寿研究所Matt Kaeberlein教授对《自然》表示。 但他同样担忧，这项技术仍处于非常早期的阶段，出现灾难性副作用的可能性很高。 “返老还童针” Life Biosciences成立于2017年，由哈佛医学院遗传学系教授、抗衰老专家David Sinclair联合创立。 根据公司官网，Life...
"I was introverted and just wanted to hide in my bedroom." Laura Cox learned everything by copying others on YouTube - but now she's writing her own script
Laura Cox, studio portrait. French guitarist and singer Laura Cox started her YouTube channel in 2006. Driven by a teenage obsession with Slash, Mark Knopfler and Angus Young, she started posting cover versions of their songs, shot in her bedroom on a basic webcam. Two decades later, now aged 35, she has recently released album number four, Trouble Coming, written entirely by herself and recorded with hot French production duo No Money Kids.
Laura Cox learned everything by copying others on YouTube
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Beyond the poster: We need brave policy on physical activity – not another campaign
Movement is one of the most powerful forms of medicine we have. So why do we keep treating it as an optional extra – and reaching for the easy solutions instead of the brave ones? Earlier this parliament, the Chief Medical Officer made a deliberately provocative point to MPs. Put a park bench in the right place five years ago, he suggested, and the cancer you are now treating in a clinic might never have happened at all.
"I was introverted and just wanted to hide in my bedroom." Laura Cox learned everything by copying others on YouTube - but now she's writing her own script
Top Gun: Maverick 8 hours ago Actor James Handy stabbed to death in Los Angeles NBC News - By Phil Helsel and Emmy Beck-Aden • 8h Handy played the bartender Jimmy in “Top Gun: Maverick,” Milton Briggs in “Arachnophobia” and other characters.
Long lives, short changed
Around 15 million working-age people are not saving enough for retirement – yet the Second Pensions Commission’s interim report suggests the policy response may arrive too late for the generation most at risk.
The King’s Speech 2026: does the government understand demographic change?
The word “ageing” does not appear once in today’s King’s Speech briefing notes – yet demographic change is the single most predictable force reshaping Britain’s public services, economy and society over the coming decades. Drawing on ILC’s research on longevity and healthy ageing, David Sinclair asks whether a government with forty-plus bills and serious legislative ambition has nonetheless produced an agenda that is, in important ways, a generation out of date. Huge legislative ambition.
Healthy ageing and NHS sustainability. Can the UK manage its way out of increasing health costs?
The UK spends around a third of what the US does on healthcare per person – but that gap masks a system under severe strain. Drawing on ILC’s research on healthy ageing and prevention, David Sinclair argues that lower spending is not the same as efficiency, and asks what it would actually take to build a health system that keeps us healthier as we age – rather than simply managing the consequences of failing to do so.
My cholesterol, my AI doctor and the future of expert advice
A borderline cholesterol result, an NHS app notification with no follow-up, and an AI that explained his blood test results more clearly than his GP. Drawing on ILC’s research on functional foods, financial advice and the opportunities of AI, David Sinclair reflects on what happens when technology starts doing the experts’ job better than the experts – and asks what that means for the future of healthcare, financial advice and the institutions that regulate them.
“When Eric Clapton left, we tried different guitarists. Peter Green told me he was better than everybody else. Once I heard him play, I realised he was”: How the most influential British blues band of the 60s replaced one brand new guitar god with another
3 hours ago Princess Beatrice and Princess Eugenie skipped Easter church service amid their dad Andrew Mountbatten-Windsor's legal troubles. The princesses were notably absent from the royal family's traditional gathering at St. George's Chapel, Windsor Castle, for Easter church service, after the former Prince …
Will you get into a driverless car?
David Sinclair, ILC Chief Executive, argues that driverless cars will change why, when and where we travel – and the bigger impact won’t in London and our big cities. The eagle eyed among you may have noticed more Waymo autonomous vehicles on the streets of London over the past few weeks. Following the passing of the UK Government’s Automated Vehicles Act, trials and tests are scaling up and we might be able to book our own robotaxis by the end of the year.
David Sinclair: Aging can be reversed, gene therapy is key to rejuvenation, and we may live into the twenty-second century | The Diary of a CEO
Aging is not an inevitable process and can be reversed. — David Sinclair Sinclair challenges the belief that aging is a natural and acceptable process. I reject the idea that aging just because it’s natural is acceptable. — David Sinclair Reversing aging could cure major diseases like Alzheimer’s and cancer. When you reverse aging diseases like Alzheimer’s cancer heart disease go away. — David Sinclair Understanding aging could have the biggest impact on human health in history.
The 11 Best Electric Toothbrushes for Whitening in 2026: Dentist-Tested & Reviewed
Buying guide11 products tested Find the best electric toothbrush for whitening in 2026. Expert reviews of Oral-B iO, Sonicare DiamondClean, and top-rated picks for every budget. By Eleanor Vance, Health & Beauty Editor · Reviewed by David Sinclair Updated March 24, 2026Reviewed by David Sinclair, Managing Editor on March 24, 202614 min read Editorial score Affiliate disclosure: We may earn a commission when you buy through links on this page.
Turning back time: a comprehensive list of interventions that decrease next-generation epigenetic aging clocks in humans
Abstract Epigenetic aging clocks estimate age from DNA methylation patterns and have become central tools in longevity research. More recently, next-generation clocks have been developed to better compensate for the known divergence between chronological age and epigenetic age in ways that relate to lifestyle, health, and age-related disease.
Konec stárnutí: Proč stárneme a proč už nemusíme
Domů Knihy Konec stárnutí: Proč stárneme a proč už nemusíme Přehled Říká se, že stáří je přirozené a jeho následky neodvratitelné. Říká se, že poslední desetiletí života jsme odsouzeni trpět nemocemi. Kdo by chtěl žít do sta let, když nás čeká jen bolestné přežívání a žádná zábava? David Sinclair spolu s dalšími předními odborníky na dlouhověkost však toto paradigma mění, když dokazuje, že STÁRNUTÍ JE NEMOC, KTEROU LZE LÉČIT. Autor odhaduje, že se i vy dožijete sta let.
"Future generations will consider it one of the most important recordings of all time." Rising Southern rock star Marcus King picks the soundtrack of his life
Marcus King posing in the wilderness. Marcus King has come a long way since he first visited the UK as a 20-year-old guitar prodigy at The O2 Bluesfest in 2016. Now a Grammy-nominated artist and one of the defining voices of modern southern rock, the South Carolina-born singer/ guitarist has poured heart and history into his new album, Darling Blue.
Rising Southern rock star Marcus King picks the soundtrack of his life
Marcus King, a Grammy-nominated artist and defining voice of modern southern rock, has released his new album "Darling Blue" which explores country-folk, psychedelic rock, and Motown-coloured R&B at Capricorn Studios in Macon, Georgia.
"When people hear my versions of pop songs, they're shocked. They never expect to hear Adele sound like that." Meet Solomon Hicks, the New York guitarist bringing the blues to a new audience
Solomon Hicks holding a guitar (studio portrait). A 30-year-old guitar prodigy from New York who’s grown up in public, Solomon Hicks is still figuring out how to make the blues his own. On his second album, How Did I Ever Get This Blue?, he lets gratitude and good vibes do the talking, with a sound and style that is more about reassurance than revolution. “I was exposed to so many genres,” he says.
Rethinking Retirement: public policies to support life changes | LSE Festival
Prior to retiring people rarely consider these questions, and there is little of a public policy framework to help them do so. How much do we understand – or anticipate - the psychological life-change around moving from a full-time executive role to something else? The path to retirement is sometimes direct, sometimes voluntary and rarely what we think it will be.
Meet Solomon Hicks, the New Yorker bringing the blues to a new audience
Solomon Hicks, a 30-year-old guitar prodigy from New York, releases his second album "How Did I Ever Get This Blue?" showcasing a sound and style focused on reassurance rather than revolution. The album features a mix of traditional blues songs by artists like Bobby 'Blue' Bland and John Lee Hooker, as well as unexpected covers of pop songs by Adele and Bruno Mars, all performed with a polished, all-star lineup.
"When people hear my versions of pop songs, they're shocked. They never expect to hear Adele sound like that." Meet Solomon Hicks, the New York guitarist bringing the blues to a new audience | Flipboard
10 hours ago “Feels like pure, endless hell,” the Guardian said in its review that also compared the first lady to Eva Braun. Please lower your big hat to half mast because the “Melania” documentary has been murdered by words. On Monday, the Guardian published a correction to its already scathing review of first …
Whiskey Myers: What rock'n'roll would say if it was a person
Whiskey Myers portrait. Cody Cannon sits outside his workshop in Palestine, Texas, talking down the line from a phone propped on his porch. Behind him lies the flat expanse of East Texas, where hunting, fishing and small-town family life have shaped his every move. He holds a jug at his side. He is polite, measured, even friendly, but sparing with his words.
Whiskey Myers: What rock’n’roll would say if it was a person
When you buy through links on our articles, Future and its syndication partners may earn a commission. Credit: Jay Blakesberg Cody Cannon sits outside his workshop in Palestine, Texas, talking down the line from a phone propped on his porch. Behind him lies the flat expanse of East Texas, where hunting, fishing and small-town family life have shaped his every move. He holds a jug at his side. He is polite, measured, even friendly, but sparing with his words.
"We don't rehearse - I just show the band my notes and it becomes something else": Garage queen Holly Golightly on new music, Jack White and the black tongue hex
Holly Golightly in sunglasses, leaning on a fence. Holly Golightly has been a survivor on the British garage-band circuit since the 90s, releasing 13 solo albums and more than 20 collaborative records. Long associated with Billy Childish and the Medway scene in Kent, she came to prominence with the riot grrrl-spirited Thee Headcoatees before striking out on her own and later with roots-rock duo The Brokeoffs.
Holly Golightly on new music, Jack White and the black tongue hex
Generate Key Takeaways When you buy through links on our articles, Future and its syndication partners may earn a commission. Credit: Damaged Goods Holly Golightly has been a survivor on the British garage-band circuit since the 90s, releasing 13 solo albums and more than 20 collaborative records.
"She was like a caged animal let loose, commanding the stage like she'd been doing it forever": Meet Hollow Souls, the rising blues rockers making a big noise | Flipboard
The band who ruined the 1960s, according to David Crosby: “On a grotesque, negative ego trip” Follow us on Google Discover When kids started to become increasingly obsessed with music in the 1960s, they essentially given a choice of two bands …
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