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Deepesh Kumar Gupta on Muck Rack

Deepesh Kumar Gupta

As seen in: Cell Reports, The Journal of Clinical Investigation
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Articles

Transcriptional analysis of primary ciliary dyskinesia airway cells reveals a dedicated cilia glutathione pathway

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By JCI Insight, Jeffrey R Koenitzer, Deepesh Kumar Gupta, Wang Kyaw Twan
| The Journal of Clinical Investigation
ResearchCell biologyPulmonology Open Access | 10.1172/jci.insight.180198 JCI Insight. https://doi.org/10.1172/jci.insight.180198. Copyright © 2024, Koenitzer et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF Abstract Primary ciliary dyskinesia (PCD) is a genetic condition that results in dysmotile cilia.
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The TERB1 MYB domain suppresses telomere erosion in meiotic prophase I

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By Kexin Zhang, Agata Tarczykowska, Devon F Pendlebury, Deepesh Kumar Gupta
| Cell Reports Verified
Highlights • The TERB1 MYB domain has lost its canonical DNA-binding activity • The TERB1 MYB domain localizes cohesin and axial element proteins at telomeres • The TERB1 MYB domain remodels axial elements in the early-to-late pachytene transition • The TERB1 MYB domain suppresses meiotic telomere erosion Summary The meiosis-specific telomere-binding protein TERB1 anchors telomeres to the nuclear envelope and drives chromosome movements for the pairing of homologous chromosomes.
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