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Delphine Sicard on Muck Rack

Delphine Sicard

As seen in: Nature, MDPI, The Conversation, La Dépêche, Science Magazine, BioRxiv, Mary Ann Liebert, Inc.
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Articles

Durotaxis is a driver and potential therapeutic target in lung fibrosis and metastatic pancreatic cancer - Nature Cell Biology

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By Maria-Anna Chrysovergi, Fei Liu, Zebin Xiao, Mark Anthony Leon-Duque, Delphine Sicard, Tejaswini S. Reddi, Edward Chaum, Kaveh Daneshvar, Allan C. Mullen, David Ting, Eric White, Raghu Kalluri, Christina M. Woo, Ellen Puré, Wolfgang H. Goldmann, Adam Engler
| Nature Verified
Abstract Durotaxis, cell migration along stiffness gradients, is linked to embryonic development, tissue repair and disease. Despite solid in vitro evidence, its role in vivo remains largely speculative. Here we demonstrate that durotaxis actively drives disease progression in vivo in mouse models of lung fibrosis and metastatic pancreatic cancer. In lung fibrosis, durotaxis directs fibroblast recruitment to sites of injury, where they undergo mechano-activation into scar-forming myofibroblasts.
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S. cerevisiae serves as keystone species for spoilage resistance in experimental synthetic wine yeast communities

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By Alanna M. Leale, Eleonore Pourcelot, Stéphane Guezenec, Delphine Sicard
| BioRxiv
Abstract Species diversity is a commonly stated contributor to the fate of an invader, and thus community resistance, in both microbial and non-microbial communities. Termed the diversity-invasion hypothesis, a positive relationship between diversity and resistance to invasion is observed when an introduced species exhibits lower levels of survival in resident communities with higher species richness.
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S. cerevisiae serves as keystone species for spoilage resistance in experimental synthetic wine yeast communities

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By Alanna M. Leale, Eleonore Pourcelot, Delphine Sicard, Stéphane Guezenec
| BioRxiv
Abstract Species diversity is a commonly stated contributor to the fate of an invader, and thus community resistance, in both microbial and non-microbial communities. Termed the diversity-invasion hypothesis, a positive relationship between diversity and resistance to invasion is observed when an introduced species exhibits lower levels of survival in resident communities with higher species richness.
Open in Who Shared Issue with article?
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