Dolores Hambardzumyan
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Get in touch with Dolores
Contact Dolores, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck RackActions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Learning the cellular origins across cancers using single-cell chromatin landscapes - Nature Communications
Abstract Deciphering the pre-malignant cell of origin (COO) of different cancers is critical for understanding tumor development and improving diagnostic and therapeutic strategies in oncology. Prior work demonstrates that somatic mutations preferentially accumulate in closed chromatin regions of a cancer’s COO.
BRAF/MEK inhibition induces cell state transitions boosting immune checkpoint sensitivity in BRAFV600E-mutant glioma
|
Keywords BRAF V600E high-grade glioma BRAF and MEK inhibitor adaptation immune checkpoint inhibition programmed death-ligand 1 cell state transitions Galectin-3 T cell modulation Introduction Brain tumors cause the most years of life lost among cancers and are the leading cause of cancer-related death in children.1,2,3,4 Unlike other cancers, targeted therapies for brain tumors remain limited, with notable exceptions including BRAF (v-raf murine sarcoma viral oncogene homolog B1) and IDH...
By Yao Xing, Dena Panovska, Jong-Whi Park, Stefan Grossauer, Katharina Koeck, Brandon Bui, Emon Nasajpour, Jeffrey J. Nirschl, Zhi-Ping Feng, Pierre Cheung, Pardes Habib, Ruolun Wei, Jie Wang, Wes Thomason, Michelle Monje, Joanne Xiu, Alexander Beck, Katharina Weber, Patrick N. Harter, Michael Lim, Kelly B. Mahaney, Laura M. Prolo, Gerald A. Grant, Xuhuai Ji, Kyle Walsh, Dolores Hambardzumyan, Claudia K. Petritsch
|
Cell Reports Medicine
Verified
Glioblastoma microenvironment-from biology to therapy
7,8 1Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, Georgia 30322, USA; 2Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia 30322, USA; 3Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA; 4The Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, Ohio 43205, USA; 5Department of Pediatrics, The Ohio State...
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Dolores
Contact Dolores, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack