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Dzmitry Padhorny

As seen in: Cell Press
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Articles

Ligand interaction landscape of transcription factors and essential enzymes in E. coli

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By Hui Peng, Sergei Kotelnikov, Megan Egbert, Shany Ofaim, Grant Stevens, Sadhna Phanse, Mikhail Ignatov, Shubham Dutta, Mohamed Taha Moutaoufik, Hiroyuki Aoki, Neal Kewalramani, Jianxian Sun, Yufeng Gong, Andrey Alekseenko, Kathryn Porter, George Jones, Irina A. Rodionova, Hongbo Guo, Suprama Datta, Milton H. Saier, Mark Crovella, Sandor Vajda, Gabriel Moreno-Hagelsieb, John Parkinson Verified, Daniel Segrè, Mohan Babu, Dima Kozakov, Andrew Emili, Tatiana Saccon, Zoe Istace, Dzmitry Padhorny, Gennady Poda, Oxana Pogoutse
| Cell Press Verified
Keywords LP/MS protein-metabolite interactions protein-ligand binding pocket molecular docking precision structural modeling enzymes transcription factors chemical probe multi-modal interactome dynamic network Introduction Protein-metabolite interactions (PMIs) underlie many, if not all, biochemical pathways, including the adaptive physiological responses involving transcriptional regulation and metabolic remodeling.
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