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Eileen Torres

As seen in: CNN, MSN Canada, New York Daily News, BioRxiv, Cell Press, Crain's New York Business, amNewYork, Gotham Gazette, sei.org, City Limits and
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Articles

The people of the Bronx are joining together

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By Eileen Torres, Haji Dukuray
| New York Daily News Verified
Feb. 5 was just another frigid Thursday night for most New Yorkers. But for the two of us, it was a night to remember. We had the honor of co-chairing a founding assembly of The Bronx First — a new citizens’ power organization in our borough. More than 1,500 of our fellow Bronx residents filled the chairs and bleachers of the Rose Hill Gym at Fordham University.
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The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway

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By Sarah Naguib, Chloe Lopez-Lee, Eileen Torres, Se-In Lee, Jingjie Zhu, Daphne Zhu, Kendra M. Norman, Mingrui Zhao, Yohannes A Ambaw, Rodrigo Munoz-Castaneda, Wei Wang, Tark J. Patel, Maitreyee Bhagwat, Rada Norinsky, Sue-Ann Mok, Tobias C. Walther, Robert V. Farese, Wenjie Luo, Subhash C. Sinha, Zhuhao Wu, Li Fan, Shiaoching Gong
| Cell Press Verified
Open GPT Console Open Oracle Keywords Refresh Values Property Value Status Version Ad File Disable Ads Flag Environment Moat Init Moat Ready Contextual Ready Contextual URL Contextual Initial Segments Contextual Used Segments AdUnit SubAdUnit Custom Targeting Ad Events Invalid Ad Sizes
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APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition

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By Sarah Naguib, Chloe Lopez-Lee, Eileen Torres, Se-In Lee
| BioRxiv
Abstract The Christchurch mutation (R136S) on the APOE3 (E3S/S) gene is associated with attenuation of tau load and cognitive decline despite the presence of a causal PSEN1 mutation and high levels of amyloid beta pathology in the carrier1. However, the specific molecular mechanisms enabling the E3S/S mutation to mitigate tau-induced neurodegeneration remain unclear. Here, we replaced mouse ApoE with wild-type human E3 or E3S/S on a tauopathy background.
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