Emmanuel J. Barbeau

Abstract Whether the brain encodes the subjective value of pleasant and unpleasant situations via a single integrated circuit or through distinct pathways remains unresolved. How such signals guide choice across contexts also remains unclear. To address these questions, we recorded intracerebral activity from participants who rated pleasant and unpleasant scenarios and then made binary choices across domains and frames.

Keywords memory population spiking network oscillations hippocampus medial temporal lobe human brain ripples single neurons theta intracranial EEG Introduction Memory unfolds across an extended processing arc that spans experience and time, from learning through consolidation to recall.1,2,3 At the core of the brain-memory circuitry is the hippocampus, whose neurons support the representation of relationships between stimuli and events.4,5,6,7,8 During learning, hippocampal activity gives...

Abstract The thalamus has a key role in mediating cortical–subcortical interactions but is often neglected in neuroimaging studies, which mostly focus on changes in cortical structure and activity. One of the main reasons for the thalamus being overlooked is that the delineation of individual thalamic nuclei via neuroimaging remains controversial. Indeed, neuroimaging atlases vary substantially regarding which thalamic nuclei are included and how their delineations were established.