Eric Welsh on Muck Rack

Eric Welsh

Verified
British Columbia
As seen in: Hope Standard, Wiley Online Library, Science Magazine, Cell Chemical Biology, Mary Ann Liebert, Inc., Abbotsford News, Kelowna Capital News, Victoria News, Surrey Now-Leader, Nanaimo News Bulletin, AHLA Connections and
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Articles

Cancer-associated fibroblasts confer ALK inhibitor resistance in EML4-ALK-driven lung cancer by concurrent integrin and MET signaling

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By Qianqian Hu, Adam Boulton, Nicholas Venetos, Bina Desai, Daria Miroshnychenko, Xueli Li, Eric Welsh Verified, Bin Fang, Gabriela Wright, Neelkamal Chaudhary, Robert C. Doebele, John M. Koomen, Eric B. Haura, Andriy Marusyk, Uwe Rix, Jodi L. Kroeger
| Science Magazine Verified
Editor’s summary Non–small cell lung cancer (NSCLC) often develops resistance to ALK inhibitors that target oncogenic fusion proteins because of growth factors secreted from cancer-associated fibroblasts (CAFs) in the tumor stroma. Hu et al. found that secreted soluble factors did not fully account for drug resistance when CAFs were cocultured with NSCLC cells.
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Dual targeting of RET and SRC synergizes in

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By Bin Fang, Eric Welsh Verified, Juhyeon Son, Nicole V. Bremer
| Wiley Online Library Verified
GDNF glial cell line-derived neurotrophic factor MAPK mitogen-activated protein kinase mTORC1 mTOR complex 1 NSCLC non-small cell lung cancer PTC papillary thyroid carcinoma RET rearranged during transfection RET+ RET fusion-positive RTK receptor tyrosine kinase siRNA small interfering RNA TKI tyrosine kinase inhibitor 1 Introduction Rearranged during transfection (RET) is a receptor tyrosine kinase (RTK), which is important for the development of normal enteric nervous systems and embryonic...
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Local Fire Chiefs Weigh in on New Safety Guidelines Proposed by Federal Government

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By Eric Welsh Verified
| Ludington Daily News Verified
The U.S. Department of Labor’s Occupational Safety and Health Administration (OSHA) has drawn up a proposal to overhaul the safety and health standards for firefighters, emergency medical service providers and other emergency first responders known as the “Fire Brigades” standard. This has some fire agencies across the country worried about the negative financial impact this could have on some smaller fire departments.
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