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Estelle Barbier on Muck Rack

Estelle Barbier

As seen in: Nature, Frontiers, Science Magazine, Cell Press
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Articles

Global changes in gene expression and splicing in alcoholic liver disease

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By Ilya Blokhin, Derek Van Booven, Josepmaria Argemi, Mengying Li, J. Rao, Estelle Barbier, Markus Heilig, Jin Cheng, Antoine Douaihy, Ramon Bataller, Claes Wahlestedt
| Nature Verified
Abstract Alcohol use disorder is a widespread illness commonly leading to alcoholic liver disease (ALD) and cirrhosis with an increased incidence of hepatocellular carcinoma (HCC), but the mechanisms of alcohol-related oncogenesis in the liver are incompletely understood. We tested the hypothesis that ALD predisposes to HCC via dysregulation of splicing.
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Leptin Gene and Leptin Receptor Gene Polymorphisms in Alcohol Use Disorder: Findings Related to Psychopathology

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By Clinical Psychoneuroendocrinology, Johns Hopkins, Estelle Barbier, Mauro Ceccanti
| Frontiers
Introduction Alcohol use disorder (AUD) is highly prevalent in the U.S., affecting ~14.1 million adults (1). It is frequently co-morbid with other addictive and psychiatric disorders, and there is substantial evidence suggesting a bidirectional relationship between AUD and other psychopathologies (2).
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A molecular mechanism for choosing alcohol over an alternative reward

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By Affective Neuroscience, Estelle Barbier, Eric Augier, Russell S. Dulman
| Science Magazine Verified
“Only” about 10 to 15% of people exposed to alcohol develop alcohol-related problems. The behavioral repertoire of people confronted with opportunities to consume alcohol involves numerous choices between this drug reward and healthy alternatives. Augier et al. established a choice procedure that begins to address alcohol addiction in rats (see the Perspective by Spanagel).
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