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Esther Yang

As seen in: Medium, Nature, South China Morning Post, The BMJ, Emerald Publishing, Canadian Family Physician, ASAM News

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Articles

Glycine-modulating Slc6a20a -ASO restores NMDA receptor function in SHANK2 and SHANK3 -mutant mice and cortical organoids

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By Junyeop Daniel Roh, Yeji Yang, Suho Lee, Esther Yang, Hyeonji Kim, Hyun Chang Kim, Jin Kim, Eunjoon Kim, Mihyun Bae, Yusang Oh, Woo-Chang Hwang, Hyunjee Jang, Hyung-Wook Choi
| Nature Verified
Abstract Suppressed NMDA receptor (NMDAR) function contributes to multiple brain disorders, including schizophrenia, autism spectrum disorder (ASD), and NMDAR encephalitis. Previous attempts to restore NMDAR activity by increasing ambient glycine, a critical co-agonist, through GlyT1 inhibition have yielded mixed outcomes, partly due to GlyT1’s extensive expression in essential brainstem regions.
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Appropriate advanced imaging for minor traumatic brain injury

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By Brian Rowe, Esther Yang, Research Scientist, Kevin Skoblenick
| Canadian Family Physician Verified
Clinical question Can clinicians safely reduce computed tomography (CT) imaging in settings where patients present with minor traumatic brain injuries (mTBIs) or concussions? Bottom line In settings where patients with acute mTBIs or concussions are assessed, efforts to reduce the use of CT scans warrant consideration. Using the Canadian CT Head Rule (CCHR) clinical decision rule (CDR), modest reductions in image ordering can be safely achieved.
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Reducing computed tomography (CT) imaging for adults with minor traumatic brain injuries in the emergency department

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By Brian H Rowe, Esther Yang, Shaina Corrick, M Hussain
| The BMJ Verified
Intended for healthcare professionals Education Reducing computed...
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