Eui Ho Kim on Muck Rack

Eui Ho Kim

As seen in: Cell Press
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Articles

Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway

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By Eui Ho Kim, Matthew Woodruff, Lilit Grigoryan, Barbara Maier, Song Hee Lee, Mario Cortese, Muktha S. Natrajan, Rajesh Ravindran, Huailiang Ma, Miriam Merad, Alexander D. Gitlin, Edward Mocarski, Joshy Jacob, Pratushya Mandal
| eLife
Abstract The squalene-based oil-in-water emulsion (SE) vaccine adjuvant MF59 has been administered to more than 100 million people in more than 30 countries, in both seasonal and pandemic influenza vaccines. Despite its wide use and efficacy, its mechanisms of action remain unclear.
Open in Who Shared Issue with article?

B Cell Competition for Restricted T Cell Help Suppresses Rare-Epitope Responses

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By Matthew Woodruff, Wei Luo, Eui Ho Kim
| Cell Press Verified
The immune system responds preferentially to particular antigenic-epitopes contained within complex immunogens, such as proteins or microbes. This poorly understood phenomenon, termed “immunodominance,” remains an obstacle to achieving polyvalent immune responses against multiple antigenic-epitopes through vaccination.
Open in Who Shared Issue with article?
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