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Editor’s summary Structured Abstract Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Editor’s summary Ceramides are a class of sphingolipid molecules involved in cell survival, stress responses, and skin membrane integrity. Goswami et al. report that ceramide synthesis also contributes to the metastasis (spread) of colorectal cancer.
A new study reveals histidine as a readily measurable and potentially modifiable metabolic biomarker for cancer risk stratification and treatment optimization, but it also highlights the challenges of translating such associations into clinically usable interventions.
ArticleOnline nowOpen access Affiliations & Notes 1Laboratory of Tumor Microenvironment and Therapeutic Resistance, Department of Oncology, KU Leuven, Leuven, 3000, Belgium 2Cell Death Research and Therapy Group, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, 3000, Belgium 3VIB Center for Cancer Biology Research, Leuven, 3000, Belgium 4Department of Applied Computational Cancer Research, Institute for AI in Medicine (IKIM), University Hospital Essen, Essen, 45147, Germany...
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