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Articles by Francesca Troilo
A structurally unique effector shared between vascular wilt fungi drives cotton and olive defoliation
Abstract Defoliating (D) strains of the vascular wilt fungus Verticillium dahliae cause severe yield losses in cotton and olive, but the genetic basis of this pathotype remained unknown. Using comparative genomics, functional genetics, structural analysis, and phylogenomics, we identify a D-pathotype–specific genomic region encoding two duplicated secreted effector genes.
α-ketoglutarate/succinate ratio imbalance impairs thymine DNA glycosylase function and base excision repair process increasing susceptibility to pancreatic cancer | Cell Death & Disease
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Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, with chronic metabolic disorders increasing risk and severity. Prolonged exposure to altered metabolism changes specific metabolite levels, impacting epigenetic landscape contributing neoplastic lesion acquisition.
By Silvia Malatesta, Virginia Vigiano Benedetti, Emanuela Salviati, Barbara Illi, Isabella Manni, Emanuele Middonti, Valerio Licursi, Francesca Troilo, Gianni Colotti, Lina Cipolla, Simone Sabbioneda, Livia Perfetto, Giulia Piaggio, Federico Bussolino, Federica Di Nicolantonio, Pietro Campiglia, Eduardo Sommella, Mattia Mori, Chiara Cencioni, Francesco Spallotta
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Nature
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Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate
Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate Candice Gautier, Francesca Troilo, Florence Cordier, Francesca Malagrinò, Angelo Toto, Lorenzo Visconti, Yanlei Zhu, Maurizio Brunori, Nicolas Wolff, Stefano Gianni Proceedings of the National Academy of Sciences Aug 2020, 202004138; DOI: 10.1073/pnas.2004138117
Templated folding of intrinsically disordered proteins
Angelo Toto‡, Francesca Malagrinò‡, Lorenzo Visconti‡, Francesca Troilo‡, Livia Pagano‡, Maurizio Brunori‡, Per Jemth§1 and Stefano Gianni‡2 ‡Istituto Pasteur—Fondazione Cenci Bolognetti, Dipartimento di Scienze Biochimiche “A.
Templated Folding of Intrinsically Disordered Proteins"
Angelo Toto1, Francesca Malagrinò1, Lorenzo Visconti1, Francesca Troilo1, Livia Pagano1, Maurizio Brunori2, Per Jemth3 and Stefano Gianni1* 1Univ.
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