Froylán Ibarra-Velarde

Ayuda Buscar en la ayuda Buscar en la ayuda Histopathology and blood biochemical in sheep treated with an experimental intramuscular fasciolicide Arias-García, Rosa [1] ; Ibarra-Velarde, Froylán [1] ; Vera-Montenegro, Yolanda [1] ; Flores-Ramos, Miguel [2] ; Hernández-Campos, Alicia [3] ; Leyva-Gómez, Gerardo [3] [1] Departamento de Parasitología. Universidad Nacional Autónoma de México. Ciudad de México. México [2] Escuela Nacional de Estudios Superiores- Unidad Mérida.

Section snippets B-cell epitope prediction The BepiPred-2.0 server (http://tools.iedb.org/bcell/) was used for the prediction of the 557 amino acid-long linear B-cell epitopes of the chimeric proteins. This server is trained on epitope data derived from crystal structures and on a large collection of linear epitopes downloaded from the IEDB database, resulting in improved predictive power. Residues with scores above 0.5 (default threshold) are predicted to be B-cell epitopes.

1. Introduction Fasciola hepatica and gastrointestinal nematodes (GIN) are common worldwide parasite infections in ruminants. They are relevant because of the large economic losses that occur in livestock worldwide [1]. On the other hand, for decades, chemical control has been the main strategy used to address these diseases. Several options depend on a wide number of products, such as clorsulon, nitroxinil, closantel, albendazole, triclabendazole or oxyclozanide [2].