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Gad Getz

As seen in: Nature, Genome Biology, Science Magazine, BioRxiv, Cell Press, EIN News, Broad Institute, EIN Presswire, Drug Target Review
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Articles

Publisher Correction: Tumor transcriptional state predicts survival in immune-checkpoint-blockade-treated glioblastoma

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By Jack Ghannam, Julian Bryan, Jakob Weiss, Daniel Kovarsky, David Merrell, Conor Messer, Kristy Schlueter-Kuck, Geoffrey G Fell, Mary Jane Lim-Fat, Gilbert Youssef, Rifaquat Rahman, Lei Qin, J. Thomas Janes III, McKayla Van Orden, Kathleen L. Pfaff, Andrew Gans Verified, Emma Lin, Raymond Y. Huang, Brian P. Danysh, Laxmi Parida, Shuqiang Li, Patrick Y Wen, E. Antonio Chiocca, Donna S. Neuberg, Keith L. Ligon, Itay Tirosh, David A Reardon, Gad Getz, Catherine J. Wu
| Nature Verified
Correction to: Nature Cancer https://doi.org/10.1038/s43018-026-01179-2, published online 3 June 2026. In the version of the article initially published, in the Abstract, “we profiled 181 ICB-treated GBM samples with bulk DNA sequencing” should have read “we profiled 181 ICB-treated GBM cases using bulk DNA sequencing”.
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Tumor transcriptional state predicts survival in immune-checkpoint-blockade-treated glioblastoma

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By Jack Ghannam, Julian Bryan, Jakob Weiss, Daniel Kovarsky, David Merrell, Conor Messer, Kristy Schlueter-Kuck, Geoffrey G Fell, Mary Jane Lim-Fat, Gilbert Youssef, Rifaquat Rahman, Lei Qin, Kathleen L. Pfaff, Andrew Gans Verified, Emma Lin, Raymond Y. Huang, Brian P. Danysh, Laxmi Parida, Shuqiang Li, Patrick Y Wen, E. Antonio Chiocca, Donna S. Neuberg, Keith L. Ligon, Itay Tirosh, David A Reardon, Gad Getz, Catherine J. Wu, J. Thomas Janes III, McKayla Van Orden
| Nature Verified
Abstract The determinants of immune checkpoint blockade (ICB) response in glioblastoma (GBM) with wild-type isocitrate dehydrogenase remain poorly understood. Here we profiled 181 ICB-treated GBM samples with bulk DNA sequencing, bulk RNA sequencing and single-nucleus RNA sequencing to investigate the genomic features associated with ICB outcomes.
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Clinical validation of a high-performance somatic exome sequencing assay: from target-enrichment strategy to variant calling

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By Junko Tsuji, Micah Rickles-Young, Justin Abreu, Alyssa Friedman, Caroline Petersen, J. Bryan, Konrad Scheffler, Edyta Malolepsza, Mark Fleharty, Katie Larkin, Kenneth J. Livak, Shuqiang Li, David A Reardon, Catherine J. Wu, Patrick A. Ott, Heidi Rehm, Max Jan, Chip Stewart, Gad Getz, Varun Jain, Severine Catreux, Carrie L. Cibulskis, Niall J Lennon, Taylor O’Connell, Theo Heyns, Fanny Dao
| Nature Verified
Abstract Clinical whole-exome sequencing (WES) has revolutionized clinical diagnostics by enabling scalable, cost-effective molecular profiling to detect somatic variants and identify novel therapeutic targets. In particular, the clinical evaluation of somatic variants relies on both high-quality sequencing data and robust variant detection with rapid turnaround times.
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