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Keywords polygenic risk score family history coronary heart disease risk prediction risk reclassification prevention coronary artery disease risk assessment Get full text access Log in, subscribe or purchase for full access. References 1. GBD 2021 Forecasting Collaborators Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021 Lancet. 2024; 403:2204-2256 2.
Abstract Electronic health records (EHRs) contain extensive multidimensional patient data, presenting challenges for the discovery of novel and meaningful clinical patterns. Unsupervised clustering of high-dimensional clinical data holds great potential for identifying novel clinical patterns. Here, we performed unsupervised clustering and characterized 100,272 patients in the Electronic Medical Records and GEnomics (eMERGE) Network.
PerspectiveOnline nowOpen access Affiliations & Notes 1Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA 2Harvard Medical School, Boston, MA, USA 3Center for Biomedical Ethics and Society, Vanderbilt University Medical Center, Nashville, TN, USA 4Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA 5Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA 6Institute for Genomic Health, Icahn School of Medicine at...
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