Gil Bar-Sela

Abstract The OncotypeDX 21-gene assay guides adjuvant chemotherapy decisions in early-stage, hormone receptor–positive, HER2-negative breast cancer, but cost and turnaround time limit access. This study presents a deep learning-based approach for predicting OncotypeDX recurrence scores directly from hematoxylin and eosin-stained whole slide images. Our approach leverages a deep learning foundation model pre-trained on 171,189 slides via self-supervised learning, which is fine-tuned for our task.

This version is not peer-reviewed. Myroslav Lutsyk,Jonathan Green,Igor Albitskiy,Gil Bar-Sela  * Myroslav Lutsyk,Jonathan Green,Igor Albitskiy,Gil Bar-Sela  * You are already at the latest version Phosphodiesterase type 5 inhibitors (PDE5I) are used to treat erectile dysfunction, as they increase blood flow to the penis during sexual stimulation, supporting erection maintenance. There is limited evidence that their use increases survival in various types of cancer.

This version is not peer-reviewed. Omar Badran,Idan Cohen,Gil Bar-Sela  * Omar Badran,Idan Cohen,Gil Bar-Sela  * This version is not peer-reviewed. Cancer-associated fibroblasts (CAFs) are crucial regulators of the tumor microenvironment (TME), promoting cancer progression, immune suppression, and therapy resistance.