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As seen in: Nature, The Hindu, Royal Society of Chemistry, BioRxiv, The Week (India), Emerald Publishing, The Journal of Biological Chemistry
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Articles

Metabolic regulation of RNA methylation by the m6A-reader IGF2BP3

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By gunjan sharma, Martín Gutierrez, Anthony Jones, Amit Kumar Jaiswal
| BioRxiv
Abstract The interplay of RNA modifications - deposited by "writers", removed by "erasers" and identified by RNA binding proteins known as "readers" - forms the basis of the epitranscriptomic gene regulation hypothesis. Recent studies have identified the oncofetal RNA-binding protein IGF2BP3 as a "reader" of the N6-methyladenosine (m6A) modification and crucial for regulating gene expression.
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ERFVII action and modulation through oxygen-sensing in Arabidopsis thaliana - Nature Communications

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By gunjan sharma, Agata Zubrycka
| Nature Verified
Abstract Oxygen is a key signalling component of plant biology, and whilst an oxygen-sensing mechanism was previously described in Arabidopsis thaliana, key features of the associated PLANT CYSTEINE OXIDASE (PCO) N-degron pathway and Group VII ETHYLENE RESPONSE FACTOR (ERFVII) transcription factor substrates remain untested or unknown.
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An oxygen-sensing mechanism for angiosperm adaptation to altitude - Nature

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By Mohamad Abbas, gunjan sharma, Carlos Alonso-Blanco, Michael Holdsworth
| Nature Verified
Abstract Flowering plants (angiosperms) can grow at extreme altitudes, and have been observed growing as high as 6,400 metres above sea level1,2; however, the molecular mechanisms that enable plant adaptation specifically to altitude are unknown. One distinguishing feature of increasing altitude is a reduction in the partial pressure of oxygen (pO2).
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