Guogui Sun on Muck Rack

Guogui Sun

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Articles

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By Zhihao Lu, Junye Wang, Yongqian Shu, Lianke Liu, Li Kong, Guogui Sun, Hu Liu, Wensheng Qiu, Gaofeng Li, Hui Luo, Yanqiao Zhang, Zheng Liu, Xiuwen Wang, Buhai Wang, Yinghua Ji, Guochun Cao, Tongjian Cui, Xinfang Hou, Liying Xue, Wenbin Yue
| bmj.com
Research Sintilimab versus...
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Proteasome-Independent Protein Knockdown by Small-Molecule Inhibitor for the Undruggable Lung Adenocarcinoma

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By Wei Zhou, Zhen Zhang, Libo Zhao, Guogui Sun
| American Chemical Society
Therapeutic target identification and corresponding drug development is a demanding task for the treatment of lung adenocarcinoma, especially the most malignant proximal-proliferative subtype without druggable protein kinase mutations. Using a cell-SELEX-generated aptamer, we discovered a new tumor driver protein, leucine-rich pentatricopeptide repeat-containing protein (LRPPRC), which is specifically overexpressed in the most lethal subtype of lung adenocarcinoma.
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