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Hallie Wiechman

As seen in: BioRxiv, Cell Press
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Articles

Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy

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By Catherine Phelps, Tingting Duan, Amanda Lee, Yue Zhang, Surya Pandey, Colin R. Laughlin, Aaron Rosen, Alex McPherson, Simran Randhawa, Lee Hedden, Tanner Richie, Hallie Wiechman, Mackenzie Bender, Ina Nemet, Patrick A. Zöhrer, Rachel A. Gottschalk, Kathryn H. Schmitz, Steven J. Mullett, Stacy L. Gelhaus, Diwakar Davar, Hassane M. Zarour, Reinhard Hinterleitner, jonathan badger, Richard R. Rodrigues, John A. McCulloch, Sonny T.M. Lee, Karl-Heinz Wagner, Maria G. Winter, Sebastian E. Winter, Jishnu Das, Joseph Pierre Verified, Giorgio Trinchieri, Marlies Meisel, Nathaniel B. Willis, Jake H. Shapira, Thomas Mossington
| Cell Press Verified
1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA 2Graduate Program of Microbiology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA 3Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA 4Tsinghua Medicine, School of Medicine, Tsinghua University, Beijing, China 5Center for Systems Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA 6Joint CMU-Pitt PhD Program in...
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Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy

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By Catherine Phelps, Nathaniel Willis, Tingting Duan, Amanda Lee Verified, Yue Zhang, Surya Pandey, Colin R. Laughlin, Aaron Rosen, Alex McPherson, Jake H. Shapira, Simran Randhawa, Lee Hedden, Tanner Richie, Hallie Wiechman, Mackenzie Bender, Ina Nemet, Patrick A. Zöhrer, Rachel A. Gottschalk, Kathryn H. Schmitz, Steven J. Mullett, Stacy L. Gelhaus, Diwakar Davar, Hassane M. Zarour, Reinhard Hinterleitner, Thomas Mossington, jonathan badger, Richard R. Rodrigues, John A. McCulloch, Sonny Lee, Karl-Heinz Wagner, Maria G. Winter, Sebastian E. Winter, Jishnu Das, Joseph Pierre Verified, Giorgio Trinchieri, Marlies Meisel
| Cell Press Verified
Keywords exercise microbiota microbiota metabolite melanoma immune checkpoint inhibitor formate FMT CD8 T cells Nrf2 Get full text access Log in, subscribe or purchase for full access. References 2. Ligibel, J.A. ∙ Bohlke, K. ∙ May, A.M. ... Exercise, Diet, and Weight Management During Cancer Treatment: ASCO Guideline J. Clin. Oncol. 2022; 40:2491-2507 3. Campbell, K.L. ∙ Winters-Stone, K.M. ∙ Wiskemann, J. ...
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Eubacterium rectale detoxification mechanism increases resilience of the gut environment

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By Tanner Richie, Leah Heeren, Hallie Wiechman, Carson Ingold
| BioRxiv
Abstract Lachnospiraceae members were highly detected in dysbiotic IL-10 KO mice that displayed similar physiological outcomes as control mice. Lachnospiraceae is a highly diverse family of microbes that have been shown to display both commensal and pathogenic characteristics in the colon environment. We investigated the impact of genetic variation in five Lachnospiraceae strains on lowering cellular inflammation and ROS levels.
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