Han Yin
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An efficient functional screening method for anti ATP hydrolase antibody based on fluorescent probes
Abstract Antibody drugs as one of the important categories of drugs in the modern biomedicine filed have been successfully applied in various fields, such as cancer diseases and immune disorders. In the early stage of monoclonal antibody drug development, scientists need to accurately select the highly functional antibodies from the numerous candidates obtained from immunized animals for subsequent development.
Toward a Drosophila melanogaster Model of Acinetobacter baumannii Infection
You are already at the latest version Acinetobacter baumannii, a multidrug-resistant member of the ESKAPE pathogen group, poses a major global public health threat due to its persistence in clinical environments, rapid acquisition of antibiotic resistance, and limited treatment options. Although mammalian and non-mammalian infection models have advanced our understanding of A. baumannii pathogenesis, many are constrained by cost, scalability, or experimental tractability.
FOSL2-driven SASP in endometrial stroma promotes the inflammation of endometriosis
Abstract Endometriosis (EMs) is characterized by chronic pelvic inflammation, but the etiology of this inflammation remains poorly understood. The senescence-associated secretory phenotype (SASP), whereby senescent cells secrete pro-inflammatory cytokines, is a potential mechanism. This study investigates the pro-inflammatory SASP in EMs and its underlying influences.
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