Hector Keun on Muck Rack

Hector Keun

As seen in: Nature, Cell Press
Scientist & supporter of England cricket
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Articles

Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants - Nature Communications

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By Nikos Stratakis, Augusto Anguita-Ruiz, Lorenzo Fabbri, Léa Maitre, Juan Gonzalez, Juan González Verified, Sandra Andrusaityte, Xavier Basagaña, Eva Borras, Hector Keun, Jesse A. Goodrich, Regina Grazuleviciene, Barbara Heude, Wen Yuan, Eduard Sabidó, Cathrine Thomsen, Jose Urquiza, José Daniel Urquiza, Theano Roumeliotaki, Marina Vafeiadi, Mariona Bustamante
| Nature Verified
Abstract Childhood obesity poses a significant public health challenge, yet the molecular intricacies underlying its pathobiology remain elusive. Leveraging extensive multi-omics profiling (methylome, miRNome, transcriptome, proteins and metabolites) and a rich phenotypic characterization across two parts of Europe within the population-based Human Early Life Exposome project, we unravel the molecular landscape of childhood obesity and associated metabolic dysfunction.
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RBM39: A druggable metabolic sensor linking RNA splicing, transcriptional regulation, and metabolic reprogramming in cancer

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By Hector Keun
| Cell Press Verified
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Multi-omics signatures of the human early life exposome - Nature Communications

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By Léa Maitre, Mariona Bustamante, Carles Hernandez-Ferrer, Alexandros P Siskos, Carlos Ruiz-Arenas, Oliver J. Robinson, Dan Mason, Barbara Heude, Maribel Casas, Sandra Andrusaityte, Regina Grazuleviciene, Marina Vafeiadi, Cathrine Thomsen, Jose Urquiza, José Daniel Urquiza, Eva Borras, Juan Gonzalez, Juan González Verified, Hector Keun, Chung-Ho E. Lau, Dolors Pelegrí-Sisó
| Nature Verified
Local ethical committees approved the studies that were conducted according to the guidelines laid down in the Declaration of Helsinki.
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