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Articles by Higgins JP
Energy drinks in youth: Cardiovascular risk and a call to action.
Abstract <p>Energy drinks are stimulant formulations, not sports drinks, yet they are increasingly embedded in adolescent athletics, gaming, and social media. Most contain substantial caffeine plus taurine, guarana, and other bioactive ingredients whose combined effects may differ from caffeine alone.
Step-by-step guide and checklists for selecting and conducting an evidence synthesis study using a framework for approaches and methods in evidence synthesis (FRAMES)
Clinical recommendations based on a single study may produce incorrect decisions (Pigott & Polanin, 2020). Therefore, multiple studies are conducted in different settings to validate the findings of original studies. An evidence synthesis study is often used to combine findings from multiple studies to develop informed decisions for clinical practices (Campbell et al., 2023).
Sex-Specific Obesity and Cardiometabolic Disease Risks in Low- and Middle-Income Countries: A Meta-Analysis Involving 3 916 276 Individuals
Obesity is a major risk factor for severe morbidity and all-cause mortality globally. It is associated with cardiometabolic diseases such as hypertension, type 2 diabetes mellitus, dyslipidemia, and coronary heart disease (1, 2). In women, excess body weight is also associated with sex-specific conditions, such as polycystic ovary syndrome, gestational diabetes, and hypertensive disorders of pregnancy (3-5).
Does frailty status predict outcome in major trauma in older people? A systematic review and meta-analysis
Abstract The incidence of major trauma in older people is increasing. Frailty is likely to be a factor that influences the outcomes of trauma. We conducted a systematic review aiming to investigate whether frailty affects major trauma outcomes in older people and whether it is more predictive than age. Observational studies investigating frailty, major trauma severity and outcomes were eligible.
Graphical tools for network meta-analysis in STATA
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Risk of nosocomial respiratory syncytial virus infection and effectiveness of control measures to prevent transmission events: a systematic review
Review doi: 10.1111/irv.12379. Affiliations Affiliations 1 School of Social and Community Medicine, University of Bristol, Bristol, UK. 2 NIHR Health Protection Research Unit in Evaluation of Interventions at University of Bristol, Bristol, UK. 3 University of Nottingham, Nottingham, UK. 4 Public Health England, London, UK. PMID: 26901358 PMCID: PMC4910170 DOI: 10.1111/irv.12379 Free PMC article Item in Clipboard Review Influenza Other Respir Viruses.
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