James Marks
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Articles by James Marks
Quantitative profiling of basal and stress-induced ribosome collisions
Abstract Background: Ribosomes stall when they encounter problematic codons or cellular stress that perturbs translation. Stalled ribosomes can lead to the formation of ribosome collisions, also known as disomes, that engage cellular surveillance and stress signaling pathways. How many disomes form during basal conditions and how disome levels change under stress remain poorly understood. Results: We used spike-in normalized Ribo-seq and Disome-seq to quantify transcriptome-wide disome levels.
General James 'Spider' Marks: there's a strategic risk hidden inside closed AI systems Original
Trust is the foundation of every military alliance. It is essential as partnership develops and ultimately is validated on the battlefield. It is becoming even more important as artificial intelligence assumes a larger role in national security. And it’s important for U.S. leaders to recognize that the performance gap between American and Chinese AI models is narrowing rapidly.
A belt-buckle checkpoint regulates the onset of botulinum neurotoxin intoxication
Abstract Fast-acting botulinum neurotoxins (BoNTs) are highly desirable for both medical and aesthetic indications, but the underlying mechanism for the differing onset of BoNTs’ action remains unknown. Here, we demonstrate that the “belt” of BoNTs, a largely unstructured loop wrapping around their catalytic light chain (LC), is key to onset of intoxication.
North Dakota’s Oil Milestone Marks 75 Years of Prosperity
In July, America will celebrate the 250th anniversary of its founding. This summer also marks an important milestone for North Dakota: the 75th anniversary of the first major oil discovery in the state. Since that moment, energy has become the cornerstone of the North Dakota economy. Prior to 1951, North Dakota was primarily known for wheat fields, not oil fields, with the state generally ranking first or second in annual wheat production.
The next front is already here in war against Iran Original
Opinion>Opinions - Cybersecurity The views expressed by contributors are their own and not the view of The Hill by James "Spider" Marks, opinion contributor - 03/20/26 12:00 PM ET by James "Spider" Marks, opinion contributor - 03/20/26 12:00 PM ET Share LinkedIn Email Getty Images Wars do not end when the bombs stop falling. They evolve. After 18 days of sustained U.S. and Israeli strikes, Iran’s air force is grounded. Its navy is at the bottom of the Gulf.
JAMES "SPIDER" MARKS: Strengthening America’s defense starts with stronger rail
The foundation of any great military power extends beyond weaponry and manpower. Good old-fashioned logistics — how we move things — is just as essential to a prepared, competitive and modern military. From Eisenhower’s Red Ball Express in World War II to today’s defense supply chains, the ability to move materials swiftly and reliably across vast stretches is integral to our national security.
Centers for Medicare & Medicaid Services’ bidding plan hands a strategic advantage to China. That’s a risk we can’t afford.
The U.S. Department of Health and Human Services building in Washington, D.C., July 21, 2007. (Saul Loeb/AFP/Getty Images/TNS) ABOUT THE AUTHOR: James “Spider” Marks, a retired U.S. Army major general, was the senior intelligence officer for the 2003 liberation of Iraq and the former commanding general of the U.S. Army Intelligence Center. He currently serves as the director of geo-political intelligence for Academy Securities, a New York-based veteran-owned bank.
Supreme Court’s review of Louisiana coastal lawsuits essential for maintaining military readiness
The Supreme Court building in Washington. (Eric Kayne/Stars and Stripes) By James “Spider” Marks In every major contingency I have planned or executed, one truth holds. Logistics wins wars. In World War II, fuel decided outcomes. The Justice Department put it plainly. World War II was a war of oil. Six billion of the seven billion barrels the Allies consumed came from American wells.
The U.S.-EU trade deal: A strategic victory
- OPINION: Energy is a global market, and volatility follows anytime chaos, war or natural disaster strikes. Although energy markets can depend on these scenarios globally, countries must do their best to insulate themselves from supply shocks. Europe still grapples with the aftereffects of Russia’s invasion of Ukraine and its impacts on the continent’s natural gas and oil supply.
Strengthening America’s defense starts with stronger rail
U.S. Army Soldiers assigned to 2nd Brigade Combat Team, 10th Mountain Division (LI), remove equipment from the railroad tracks with a utility vehicle in preparation for rotation at the Joint Readiness Training Center (JRTC) on Fort Polk, Louisiana, Aug. 6, 2025. JRTC is designed to improve unit readiness through force-on-force exercises that prepare Soldiers for missions they may be assigned in real-world operations.
Offshore wind is a national security imperative
Wind turbines dot the coastline along a giant solar farm near Weifang in eastern China's Shandong province on March 22, 2024. (Ng Han Guan/AP) In his second inaugural address, President Donald Trump addressed our current energy challenges and solutions to bring down high prices. Trump is right; we face an energy emergency that threatens our national security.
Europe needs energy independence from Russia. Will the US make it happen?
Some pumpjacks operate while others stand idle in the Belridge oil field on November 3, 2021, near McKittrick, Calif. It’s clear that NATO does not want to rely on Russian oil and gas for fuel but is unwilling to fully abstain until they can import it from elsewhere. As the EU’s closest ally, the United States should be the nation to fill the gap left by the reduction in the access to Russian fuel.
To counter China, the US must strengthen ammunition production
Welcome to NewsBreak, an open platform where diverse perspectives converge. Most of our content comes from established publications and journalists, as well as from our extensive network of tens of thousands of creators who contribute to our platform. We empower individuals to share insightful viewpoints through short posts and comments.
To counter China, the US must strengthen ammunition production
Much has been made about the supply chain for high-end American munitions, but the same issues plague the most basic of America’s armaments: the ammunition used by US forces. In this op-ed, retired Maj. Gen. James Marks calls for Congress to support initiatives that will ensure a supply of a key component for US ammunition suppliers.
Increasing LNG Permits Is Critical to Sanctioning Russia
Share on Facebook Share on Twitter Share on LinkedIn Subscribe to RSS Print Topic: Energy Region: Europe Tags: EnergyRussiaRussia SanctionsLNGEnergy Security Vladimir Putin’s long-standing opposition to U.S. natural gas highlights its strategic value—powering our allies to allow them to reduce dependency on Russian LNG.
Biden's EV mandates hitting at U.S. 'national security' — THE MILLENNIAL PRESS
[Editor’s note: This story originally was published by Real Clear Wire.] By James Marks Real Clear Wire Normally a new year brings a renewed focus on getting things done in Washington. But with Congress accomplishing little in 2023 and attentions now shifting to the November elections, it is more prudent than ever that the policy agenda of our nation’s leaders reflect what’s best for our collective future, not politics.
Rethinking America’s Qatar alliance
James Marks Hamas’s unconscionable Oct. 7 attacks shocked and horrified decent people worldwide. But the boldness and brutality of this attack should have come as no surprise to policymakers, who have watched for years as countries in the region have offered material aid and sanctuary to the terrorist organization. With 31 Americans dead as a direct result of that attack and with still more held hostage, it may now be time for a fundamental rethinking of America’s relationships in the region.
A Rushed EV Approach Will Undermine Our National Security
Normally a new year brings a renewed focus on getting things done in Washington. But with Congress accomplishing little in 2023 and attentions now shifting to the November elections, it is more prudent than ever that the policy agenda of our nation’s leaders reflect what’s best for our collective future, not politics. Take this administration’s campaign to spread electric-vehicle (EV) technologies. There is no doubt that EVs will be part of America’s future.
A Rushed EV Approach Will Undermine Our National Security
Normally a new year brings a renewed focus on getting things done in Washington. But with Congress accomplishing little in 2023 and attentions now shifting to the November elections, it is more prudent than ever that the policy agenda of our nation’s leaders reflect what’s best for our collective future, not politics. Take this administration’s campaign to spread electric-vehicle (EV) technologies. There is no doubt that EVs will be part of America’s future.
Rethinking America’s Qatar Alliance – DC Journal - InsideSources
Hamas’s unconscionable October 7 attacks shocked and horrified decent people worldwide. But the boldness and brutality of this attack should have come as no surprise to policymakers, who have watched for years as countries in the region have offered material aid and sanctuary to the terrorist organization. With 31 Americans dead as a direct result of that attack and with still more held hostage, it may now be time for a fundamental rethinking of America’s relationships in the region.
A Robust Spectrum Pipeline Is the Key to Maintaining Global Leadership
Share on Facebook Share on Twitter Share on LinkedIn Subscribe to RSS Print Topic: Technology Region: Americas Blog Brand: Techland Tags: TechnologyChinaSpectrumMilitary5g6G At a time when tensions with China could escalate, the United States cannot afford to waver on spectrum policy. Our national security depends on it.
'Right to repair' laws could weaken U.S. cybersecurity
OPINION: Back in 2014, a Pew Research study looked at the future of the internet and found that most tech experts agreed that the proliferation of the internet would have “widespread” effects on public life by 2025. “Amplified connectivity will influence nearly everything, nearly everyone, nearly everywhere,” the authors postulated. “Amplified connectivity will influence nearly everything, nearly everyone, nearly everywhere,” the authors postulated.
Energy lessons learned from Germany
Recent events illustrate how the political popularity of renewables has driven many countries in Europe to rush blindly into their energy transitions. Traditional energy sources like oil and gas still play an essential role in modern economies. Germany provides an apt example of how overreliance on energy imports from a limited number of foreign sources can place a country in a dangerous position that risks economic hardship and outsized foreign influence.
Commentary: Germany’s example shows why we still need a mix of energy sources
The political popularity of renewables has driven many countries in Europe to rush blindly into their energy transitions. But traditional energy sources such as oil and gas still play an essential role in modern economies, and Germany provides an apt example of how enforcing broad mandates for green technologies can lead to an overreliance on energy imports from a limited number of foreign sources that placesa country in a dangerous position.
Opinion: Energy Lessons Learned From Germany – Inside Sources | Prescott eNews
Recent events illustrate how the political popularity of renewables has driven many countries in Europe to rush blindly into their energy transitions. Traditional energy sources like oil and gas still play an essential role in modern economies. Germany provides an apt example of how overreliance on energy imports from a limited number of foreign sources can place a country in a dangerous position that risks economic hardship and outsized foreign influence.
Energy Lessons Learned From Germany
Recent events illustrate how the political popularity of renewables has driven many countries in Europe to rush blindly into their energy transitions. Traditional energy sources like oil and gas still play an essential role in modern economies. Germany provides an apt example of how overreliance on energy imports from a limited number of foreign sources can place a country in a dangerous position that risks economic hardship and outsized foreign influence.
Opinion: Energy lessons learned from Germany
Recent events illustrate how the political popularity of renewables has driven many countries in Europe to rush blindly into their energy transitions. Traditional energy sources like oil and gas still play an essential role in modern economies. Germany provides an apt example of how overreliance on energy imports from a limited number of foreign sources can place a country in a dangerous position that risks economic hardship and outsized foreign influence.
DOE needs to recognize importance of US energy to national security
As the world grapples with the ongoing Russia-Ukraine conflict and the associated geopolitical tensions, the United States has an opportunity to play a leading role in supporting our allies by exporting our liquefied natural gas (LNG). The U.S. has abundant natural gas reserves and advanced energy technology, putting us in a prime position to reclaim our position as a global leader in LNG production and exports.
Don’t Ignore Chinese Legacy Chips as an Economic and Security Threat
On February 24, Commerce Secretary Gina Raimondo launched the Biden administration’s vision for implementing the CHIPS Act, encouraging semiconductor companies to apply for a piece of the $39 billion which has been devoted to reinvigorating America’s domestic chipmaking capacity.
It’s in the U.S.’s Interest To Pursue Extradition From Allies Wisely
We’re into the second year of war. Russia’s illegal war of conquest in Ukraine has demonstrated many things, but the value of the cohesive support of our allies is unequivocal. Ukraine has fought valiantly, proving wrong just about every analyst who predicted a rapid fall of Kyiv. But Ukraine’s impressive stand would have been impossible without the U.S. leading a worldwide coalition of countries. The U.S. has provided the leading share of aid by a wide margin.
Government can encourage 5G network development without running the entire show
The next generation of telecommunications, or 5G, is taking shape. The United States is going toe-to-toe with China in this high-stakes competition, with government policies encouraging multibillion-dollar investments by leading U.S. companies that will usher in revolutionary changes in how we use technology to work, learn, travel, manage health and simply stay in touch with people.
Government Can Encourage 5G Network Development Without Running the Entire Show – DC Journal - InsideSources
The next generation of telecommunications, or 5G, is taking shape. The United States is going toe-to-toe with China in this high-stakes competition, with government policies encouraging multi-billion-dollar investments by leading U.S. companies that will usher in revolutionary changes in how we use technology to work, learn, travel, manage health and simply stay in touch with people.
EIGHTEEN RETIRED MILITARY LEADERS URGE PRESIDENT BIDEN TO SUPPORT DOMESTIC ENERGY PRODUCTION Original
WASHINGTON , Sept. 28, 2022 /PRNewswire/ -- Eighteen retired military personnel from the U.S. Army, Navy, Air Force, and Marine Corps sent a letter to President Biden urging him to increase support for domestic energy development today. The former military leaders express the importance of America's role as a leader against those who would use energy resources as a weapon to destabilize the market and assert power over our allies around the globe.
As Russia Weaponizes Its Energy Dominance, US Must Create Its Own Energy Security
It’s been said that those who ignore history are doomed to repeat it. As the U.S. and the world observe in real-time the consequences of Russia’s grip over European energy supplies, a strategic stranglehold that has played no small part in Putin’s attempt to seize Ukraine, U.S. leaders must take steps to enhance our own energy security.
As Russia Weaponizes Its Energy Dominance, US Must Create Its Own Energy Security
It’s been said that those who ignore history are doomed to repeat it. As the U.S. and the world observe in real-time the consequences of Russia’s grip over European energy supplies, a strategic stranglehold that has played no small part in Putin’s attempt to seize Ukraine, U.S. leaders must take steps to enhance our own energy security.
Are paid internships the solution to inclusivity in tech?
I’ve been increasingly aware of an inclusivity in tech problem. In 2017, I came across a non-profit in LA that was tackling a big, complicated part of the problem: career opportunities for young people of color in low-income communities. Their program met kids in middle and high school and taught them how to code. Alongside that, the kids learned the soft skills they’d need to be successful working in tech.
James Marks, Author at ReadWrite
James Marks Founder & CEO I'm an entrepreneur, designer, and programmer. I've bootstrapped, raised money, built teams and sold companies, with a focus on empowering the creative class and building inclusive, durable businesses. Latest Posts From James Marks I’ve been increasingly aware of an inclusivity in tech problem. In 2017, I came across a non-profit in LA that was tackling a big, complicated part of the problem: career opportunities for young people of color in low-income communities.
History of the American Declaration of Independence
A story that starts in Strabane Gray’s Printing Press was first listed as a printing press in the middle of the 18th-century. Located behind a shop front in the heart of Strabane, the family run business provided books, pamphlets and newspapers to its local communities.
Don't let anything block US energy independence
OPINION Don't let anything block US energy independence By JAMES “SPIDER” MARKS | Special to Stars and Stripes | Published: April 9, 2021 Last week, the Ever Given was finally dislodged from the Suez Canal, freeing movement for more than 400 ships whose delay cost the global economy billions. Although the six-day blockage was considerably shorter than what many had feared, experts predict that it will still be months before residual disruptions abate.
India Shouldn't Weaponize Its Judiciary
Secretary of Defense Lloyd Austin visited India this month to forge stronger security and economic ties between our two great nations. The visit was highly significant, because it came amid the most dangerous power dynamics we have seen in the Indo-Pacific region for a generation. China is no longer a growing or emerging threat, but poses a direct danger to our regional allies and partners.
Guide vets as they use benefits they earned
OPINION Guide vets as they use benefits they earned By STEVEN HALL AND JAMES “SPIDER” MARKS | Special to Stars and Stripes | Published: February 10, 2021 It’s a new day in Washington, D.C. President Joe Biden is getting settled into the White House, a split Congress has compromised on how it will share power, and Denis McDonough has been confirmed as secretary of the Department of Veterans Affairs.
What President Biden Should Do about Hong Kong
On November 11, four moderate, pro-democracy members of Hong Kong’s Legislative Council (known as the LegCo) were disqualified under a new law permitting their expulsion for insufficient loyalty to Beijing. The 15 remaining pro-democracy members resigned in protest, leaving the LegCo—where lawmakers once debated legislation, and could block overreach by the pro-Beijing Hong Kong government—as a mere rubber-stamp for the Chinese Communist Party (CCP).
Fitness is critical to US military readiness
OPINION Fitness is critical to US military readiness By JAMES “SPIDER” MARKS | Special to Stars and Stripes | Published: November 20, 2020 As President-elect Joe Biden prepares to take office in January, he is rightfully steering the bulk of his efforts toward the ongoing COVID-19 pandemic. However, despite our internal battle against this relenting virus, global events continue to swirl around us and will test the new president and his administration.
How to Wage an Ideological Conflict with China
Both the Trump and Biden presidential campaigns vied to outdo the other in being “tough on China.” The Trump administration declassified an intelligence assessment that the Chinese Communist Party favored Biden over Trump, and Biden responded with harsh words for both President Trump and Chairman Xi. While the House and the Senate are slated to be sharply divided in the next Congress, there is broad consensus on the need to confront China.
What Biden Can Learn From Trump on China
What Biden Can Learn From Trump on China class="single-subtitle">The Trump administration raised barriers to China acquiring American dual-use technology. The Biden administration should do even more.
What Biden Can Learn from Trump on China
President-elect Joe Biden’s presidential campaign was defined in large part by extreme differentiation from the incumbent. While Trump was erratic, Biden was stable. While Trump was ruthless, Biden was compassionate. But while Biden can continue to emphasize his differences with the outgoing president on matters of character and personality, there is at least one area in which he should continue the policy begun by the Trump administration.
The U.S. Must Act Now to Curb China’s ‘Wolf Warrior Diplomacy’
For over a generation China has been on a long march to assert its dominance on the global stage. As a young foreign affairs officer in Asia and later working in U.S. military intelligence, I came to respect the Chinese’s commitment to achieving their goals. They work hard and make great sacrifices to get ahead, often by any means necessary—not the least of which is commandeering others’ ideas and engineering those to serve their ends.
New U.S. tool vs. Iran
Tensions in the Middle East escalated to a tipping point earlier this month when Iran launched ballistic missile attacks on U.S. and Coalition military forces in Iraq. The offensive, which the regime acknowledged as retaliation for a U.S. drone strike days earlier that killed Iranian general Qasem Soleimani, commander of the elite Quds Force, brought relations between the United States and Iran closer to the brink of conflict than at any time since the 1979 Iranian hostage crisis.
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