Skip to main content
James Vince on Muck Rack

James Vince

As seen in: Dailymotion, Nature, India.com, DNA India, Cell Press, Thrive Global, Sport360, Cricket Country, Journal of Cell Biology, The Journal of Biological Chemistry and

Get in touch with James

Contact James, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

James Vince’s Biography

Read Full Bio →

Hey Everyone. I am James and I am a medication expert by calling. I am here to be at your help with some basic issue. Various people are encountering a couple issues in their bodies. Some of those issues rise up out of the miseries that are to a great degree uncomfortable for them. There are various clarifications behind the agonies in the bodies. A couple people encounter the evil impacts of agonies as a result of the setbacks or surgeries and some experience the evil impacts of them in light …

Articles

Reply to ‘Single-cell evidence for PANoptosome complexes’

|
By James Vince, John Silke
| Nature Verified
In their Correspondence to our Comment (Vince, J. E. & Silke, J. The PANoptosis hypothesis examined. Nat. Rev. Mol. Cell Biol. https://doi.org/10.1038/s41580-026-00970-4; 2026)1, Tweedell and Kanneganti contend that PANoptosis is a distinct cell death pathway (Tweedell, R. & Kanneganti, T.-D. Single-cell evidence for PANoptosome complexes. Nat. Rev. Mol. Cell Biol.
Open in Who Shared Issue with article?

The PANoptosis hypothesis examined

|
By James Vince, John Silke
| Nature Verified
Danger signals have been reported to induce a PANoptosome complex, enabling the simultaneous induction of pyroptotic, apoptotic and necroptotic cell death. Here, we discuss the evidence for PANoptosis and suggest criteria to distinguish it from other hypotheses that can account for activation of multiple cell death pathways.
Open in Who Shared Issue with article?

NEDD4L-mediated Gasdermin D and E ubiquitination regulates cell death and tissue injury - Cell Death & Differentiation

|
By Sonia Shah, Jantina Manning, Yoon Lim, Raja Sundaram Ganesan, Nirmal Robinson, Seth Masters, James Vince
| Nature Verified
Abstract The membrane pore-forming gasdermin (GSDM) proteins are essential executors of pyroptosis. The GSDM family members GSDMD and GSDME can also target mitochondrial membranes, driving apoptosis. Here, we identify the ubiquitin ligase NEDD4L as a key regulator of GSDMD and GSDME, two GSDMs involved in cell death. NEDD4L ubiquitinates both these proteins to control their stability and intracellular expression levels.
Open in Who Shared Issue with article?
See all 45 articles